Preparation and SPF Evaluation of Sunscreen Cream Containing Titanium Dioxide

Titanium dioxide, a physical sunscreen, is a metal oxide which reflects and disperses incident UV radiation by an optical mechanism. Sun protect factor (SPF) indicates the level of protection from UV rays. This study aims to prepare titanium dioxide sunscreen cream and evaluate its SPF. Sunscreen cream was first prepared by emulsification method, and then mixed with titanium dioxide. As a result, the sunscreen cream loaded with 5% titanium dioxide had good visual performance, physical stability, and medium UV protection effect with SPF 20+. Keywords Titanium dioxide, sunscreen, SPF. References [1] K. Morabito, N.C. Shapley, et al. Review of sunscreen and the emergence of non‐conventional absorbers and their applications in ultraviolet protection, International journal of cosmetic science. 33(5) (2011), 385-390. https://doi.org/10.1111/j.1468-2494.2011.00654.x.[2] Schalka Sergio, Reis Vitor Manoel Silva dos. Sun protection factor: meaning and controversies, Anais brasileiros de dermatologia. 86(3) (2011) 507-515. [3] Serpone Nick, Dondi Daniele, et al. Inorganic and organic UV filters: Their role and efficacy in sunscreens and suncare products, Inorganica Chimica Acta. 360(3) (2007) 794-802. https://doi.org/10.1016/j.ica.2005.12.057.[4] COLIPA. Method for in vitro determination of uva protection, (2011), 17-19.[5] Couteau Céline, Faure Aurélie, et al. Study of the photostability of 18 sunscreens in creams by measuring the SPF in vitro, Journal of pharmaceutical and biomedical analysis. 44(1) (2007) 270-273. https://doi.org/10.1016/j.jpba.2007.01.052.[6] ISO (2010), Biological evaluation of medical devices-Part 10: Tests for irritation and skin sensitization, 10.[7] OECD (2015), OECD Guideline for testing of chemicals: Acute Dermal Irritation/Corrosion, 404.