Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Long-term outcomes of laparoscopic hepatectomy for hepatocellular carcinoma at Viet Duc University Hospital from 2019 to 2023
View through CrossRef
Abstract
Introduction: Laparoscopic liver resection is a challenging procedure, yet it is increasingly applied in the treatment of hepatocellular carcinoma (HCC), including our center. Our aim is to evaluate the impact of laparoscopic hepatectomy for hepatocellular carcinoma regarding the long-term outcomes.
Patients and Methods: A combined retrospective-prospective cohort study of 41 HCC patients who underwent laparoscopic hepatectomy at the Organ Transplantation Center, Viet Duc University Hospital from January 2019 to December 2023.
Results: Liver resection for tumors >5 cm accounted for 24.4%, with 63.4% of cases classified as high difficulty (Ban Daisuke score). The mean operative time was 192 minutes, and the intraoperative blood transfusion rate was 18.9%. The mean disease-free survival was 44.5 ± 3.19 months, with 1-, 2-, 3-, and 4-year rates of 94.4%, 87.2%, 70.6%, and 70.6%, respectively. The mean overall survival was 50.0 ± 2.30 months, with corresponding rates of 96.7%, 92.9%, 86.8%, and 86.8%. Preoperative AFP 0.5 cm were favorable prognostic factors.
Conclusions: Laparoscopic hepatectomy is a safe and effective treatment option for hepatocellular carcinoma offering significant survival benefits.
Keywords: Laparoscopic hepatectomy, Difficulty Scoring System, Hepatocellular carcinoma.
References
GLOBOCAN 2020. Cancer fact sheet: Vietnam fact sheet. Accessed April 29, 2023. https://gco.iarc.fr/today/data/factsheets/populations/704-viet-nam-fact-sheets.pdf
Balzan S, Belghiti J, Farges O, et al. The “50-50 Criteria” on Postoperative Day 5 An Accurate Predictor of Liver Failure and Death After Hepatectomy. Annals of Surgery. 2005;242(6):824-829. doi:10.1097/01.sla.0000189131.90876.9e
Dindo D, Demartines N, Clavien PA. Classification of Surgical Complications. Annals of Surgery. 2004;240(2):205-213. doi:10.1097/01.sla.0000133083.54934.ae
Johnson PJ, Berhane S, Kagebayashi C, et al. Assessment of Liver Function in Patients With Hepatocellular Carcinoma: A New Evidence-Based Approach—The ALBI Grade. Journal of Clinical Oncology. 2015;33(6):550-558. doi:10.1200/jco.2014.57.9151
Ban D, Tanabe M, Ito H, et al. A novel difficulty scoring system for laparoscopic liver resection. J Hepatobiliary Pancreat Sci. 2014;21(10):745-753. doi:10.1002/jhbp.166
Tran Cong Duy Long. Evaluation of the Role of Laparoscopic Liver Resection in the Treatment of Hepatocellular Carcinoma. Doctoral Thesis in Medicine. University of Medicine and Pharmacy at Ho Chi Minh City; 2016.
Nguyen Dinh Hieu, Nguyen Quang Nghia, Pham Van Binh. Result of laparoscopic liver resection for hepatocellular carcinoma in Nghe An oncology hospital. VMJ. 2024;536(1B). doi:10.51298/vmj.v536i1B.8822
Yoon YI, Kim KH, Cho HD, et al. Long-term perioperative outcomes of pure laparoscopic liver resection versus open liver resection for hepatocellular carcinoma: a retrospective study. Surg Endosc. 2019;34(2):796-805. doi:10.1007/s00464-019-06831-w
Yamamoto M, Kobayashi T, Oshita A, et al. Laparoscopic versus open limited liver resection for hepatocellular carcinoma with liver cirrhosis: a propensity score matching study with the Hiroshima Surgical study group of Clinical Oncology (HiSCO). Surg Endosc. 2020;34(11):5055-5061. doi:10.1007/s00464-019-07302-y
Ghielmetti M, Ramser M, Oertli D. Laparoscopic liver resection: a single-centre experience. Swiss Med Wkly. 2021;151:w20391. doi:10.4414/smw.2021.20391
Ruzzenente A, Bagante F, Poletto E, et al. A machine learning analysis of difficulty scoring systems for laparoscopic liver surgery. Surg Endosc. 2022;36(12):8869-8880. doi:10.1007/s00464-022-09322-7
Tsai KY, Chen HA, Wang WY, Huang MT. Long-term and short-term surgical outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma: might laparoscopic approach be better in early HCC? Surg Endosc. 2019;33(4):1131-1139. doi:10.1007/s00464-018-6372-0
Soubrane O, Goumard C, Laurent A, et al. Laparoscopic resection of hepatocellular carcinoma: a French survey in 351 patients. HPB. 2014;16(4):357-365. doi:10.1111/hpb.12142
Cheng CH, Lai Y, Hung HC, et al. Recurrence Patterns After Hepatectomy With Very Narrow Resection Margins for Hepatocellular Carcinoma. Front Surg. 2022;9:926728. doi:10.3389/fsurg.2022.926728.
Download file PDF
Vietnam Association for Surgery and Endolaparosurgery
Title: Long-term outcomes of laparoscopic hepatectomy for hepatocellular carcinoma at Viet Duc University Hospital from 2019 to 2023
Description:
Abstract
Introduction: Laparoscopic liver resection is a challenging procedure, yet it is increasingly applied in the treatment of hepatocellular carcinoma (HCC), including our center.
Our aim is to evaluate the impact of laparoscopic hepatectomy for hepatocellular carcinoma regarding the long-term outcomes.
Patients and Methods: A combined retrospective-prospective cohort study of 41 HCC patients who underwent laparoscopic hepatectomy at the Organ Transplantation Center, Viet Duc University Hospital from January 2019 to December 2023.
Results: Liver resection for tumors >5 cm accounted for 24.
4%, with 63.
4% of cases classified as high difficulty (Ban Daisuke score).
The mean operative time was 192 minutes, and the intraoperative blood transfusion rate was 18.
9%.
The mean disease-free survival was 44.
5 ± 3.
19 months, with 1-, 2-, 3-, and 4-year rates of 94.
4%, 87.
2%, 70.
6%, and 70.
6%, respectively.
The mean overall survival was 50.
0 ± 2.
30 months, with corresponding rates of 96.
7%, 92.
9%, 86.
8%, and 86.
8%.
Preoperative AFP 0.
5 cm were favorable prognostic factors.
Conclusions: Laparoscopic hepatectomy is a safe and effective treatment option for hepatocellular carcinoma offering significant survival benefits.
Keywords: Laparoscopic hepatectomy, Difficulty Scoring System, Hepatocellular carcinoma.
References
GLOBOCAN 2020.
Cancer fact sheet: Vietnam fact sheet.
Accessed April 29, 2023.
https://gco.
iarc.
fr/today/data/factsheets/populations/704-viet-nam-fact-sheets.
pdf
Balzan S, Belghiti J, Farges O, et al.
The “50-50 Criteria” on Postoperative Day 5 An Accurate Predictor of Liver Failure and Death After Hepatectomy.
Annals of Surgery.
2005;242(6):824-829.
doi:10.
1097/01.
sla.
0000189131.
90876.
9e
Dindo D, Demartines N, Clavien PA.
Classification of Surgical Complications.
Annals of Surgery.
2004;240(2):205-213.
doi:10.
1097/01.
sla.
0000133083.
54934.
ae
Johnson PJ, Berhane S, Kagebayashi C, et al.
Assessment of Liver Function in Patients With Hepatocellular Carcinoma: A New Evidence-Based Approach—The ALBI Grade.
Journal of Clinical Oncology.
2015;33(6):550-558.
doi:10.
1200/jco.
2014.
57.
9151
Ban D, Tanabe M, Ito H, et al.
A novel difficulty scoring system for laparoscopic liver resection.
J Hepatobiliary Pancreat Sci.
2014;21(10):745-753.
doi:10.
1002/jhbp.
166
Tran Cong Duy Long.
Evaluation of the Role of Laparoscopic Liver Resection in the Treatment of Hepatocellular Carcinoma.
Doctoral Thesis in Medicine.
University of Medicine and Pharmacy at Ho Chi Minh City; 2016.
Nguyen Dinh Hieu, Nguyen Quang Nghia, Pham Van Binh.
Result of laparoscopic liver resection for hepatocellular carcinoma in Nghe An oncology hospital.
VMJ.
2024;536(1B).
doi:10.
51298/vmj.
v536i1B.
8822
Yoon YI, Kim KH, Cho HD, et al.
Long-term perioperative outcomes of pure laparoscopic liver resection versus open liver resection for hepatocellular carcinoma: a retrospective study.
Surg Endosc.
2019;34(2):796-805.
doi:10.
1007/s00464-019-06831-w
Yamamoto M, Kobayashi T, Oshita A, et al.
Laparoscopic versus open limited liver resection for hepatocellular carcinoma with liver cirrhosis: a propensity score matching study with the Hiroshima Surgical study group of Clinical Oncology (HiSCO).
Surg Endosc.
2020;34(11):5055-5061.
doi:10.
1007/s00464-019-07302-y
Ghielmetti M, Ramser M, Oertli D.
Laparoscopic liver resection: a single-centre experience.
Swiss Med Wkly.
2021;151:w20391.
doi:10.
4414/smw.
2021.
20391
Ruzzenente A, Bagante F, Poletto E, et al.
A machine learning analysis of difficulty scoring systems for laparoscopic liver surgery.
Surg Endosc.
2022;36(12):8869-8880.
doi:10.
1007/s00464-022-09322-7
Tsai KY, Chen HA, Wang WY, Huang MT.
Long-term and short-term surgical outcomes of laparoscopic versus open liver resection for hepatocellular carcinoma: might laparoscopic approach be better in early HCC? Surg Endosc.
2019;33(4):1131-1139.
doi:10.
1007/s00464-018-6372-0
Soubrane O, Goumard C, Laurent A, et al.
Laparoscopic resection of hepatocellular carcinoma: a French survey in 351 patients.
HPB.
2014;16(4):357-365.
doi:10.
1111/hpb.
12142
Cheng CH, Lai Y, Hung HC, et al.
Recurrence Patterns After Hepatectomy With Very Narrow Resection Margins for Hepatocellular Carcinoma.
Front Surg.
2022;9:926728.
doi:10.
3389/fsurg.
2022.
926728.
Download file PDF.
Related Results
Complex Collision Tumors: A Systematic Review
Complex Collision Tumors: A Systematic Review
Abstract
Introduction: A collision tumor consists of two distinct neoplastic components located within the same organ, separated by stromal tissue, without histological intermixing...
Breast Carcinoma within Fibroadenoma: A Systematic Review
Breast Carcinoma within Fibroadenoma: A Systematic Review
Abstract
Introduction
Fibroadenoma is the most common benign breast lesion; however, it carries a potential risk of malignant transformation. This systematic review provides an ove...
Repeat Hepatectomy for Recurrent Colorectal Metastases
Repeat Hepatectomy for Recurrent Colorectal Metastases
AbstractRecurrence rates after hepatic resection in patients with colorectal metastases are reported to range from 47% to 80%. Hepatic recurrence is seen in 35% to 50% of patients....
Outcome of laparoscopy assisted pancreaticoduodenectomy at the department of gastrointestinal surgery, Viet Duc University Hospital
Outcome of laparoscopy assisted pancreaticoduodenectomy at the department of gastrointestinal surgery, Viet Duc University Hospital
Abstract
Introduction: Laparoscopic-assisted pancreaticoduodenectomy is a complex surgical procedure associated with a high rate of complications, particularly those arising from...
Evaluating the GALAD Score in Diagnosing Hepatocellular Carcinoma
Evaluating the GALAD Score in Diagnosing Hepatocellular Carcinoma
This paper aims to evaluate the GALAD score in diagnosing hepatocellular carcinoma. The paper conducted a retrospective study of 86 Hepatocellular Carcinoma patients who underwent ...
Risk prediction for Dermatomyositis-associated hepatocellular carcinoma
Risk prediction for Dermatomyositis-associated hepatocellular carcinoma
Abstract
Objective
To explore dermatomyositis signature genes as potential biomarkers of hepatocellular carcinoma and their associated molecular regulatory mechanisms.
Meth...
A <span aria-describedby="tippy-18">Comparison of Clinical Outcomes of Robot-Assisted and Conventional Laparoscopic Surgery
A <span aria-describedby="tippy-18">Comparison of Clinical Outcomes of Robot-Assisted and Conventional Laparoscopic Surgery
Background: Robot-assisted laparoscopic surgery robot-assisted surgical system has gained significant popularity over open and laparoscopic interventions. However, given its high c...
Caudate lobe-based minimally invasive anatomic hepatectomy: a retrospective study
Caudate lobe-based minimally invasive anatomic hepatectomy: a retrospective study
Abstract
Background: Anatomic hepatectomy has become a crucial surgical procedure in the liver section. The function and role of the caudate lobe in anatomic hepatectomy re...