Outcome of laparoscopy assisted pancreaticoduodenectomy at the department of gastrointestinal surgery, Viet Duc University Hospital

Abstract Introduction: Laparoscopic-assisted pancreaticoduodenectomy is a complex surgical procedure associated with a high rate of complications, particularly those arising from anastomotic leakage. The combination of laparoscopic dissection and resection with a mini-laparotomy for specimen retrieval and anastomosis construction is thought to potentially reduce perioperative morbidity. Patients and Methods: A cross-sectional descriptive case series was conducted involving 18 patients who underwent laparoscopically-assisted pancreaticoduodenectomy at the Department of Gastrointestinal Surgery, Viet Duc University Hospital, during the period from 2023 to 2025. Results: A total of 18 patients underwent laparoscopic-assisted pancreaticoduodenectomy. Among these, 55.6% were diagnosed with ampullary adenocarcinoma, 22.2% with solid pseudopapillary neoplasms of the pancreas, and 11.1% with pancreatic neuroendocrine tumors. The mean operative time was 352.44 ± 44.59 minutes. The average length of the mini-laparotomy incision was 6.78 ± 1.67 cm. Mean intraoperative blood loss was 163.89 ± 136.99 ml. Postoperative complications included pancreatic fistula (27.7%), postoperative hemorrhage (5.6%), bile leak (5.6%), chyle leak (5.6%), and gastrointestinal bleeding (5.6%). All patients were alive at the time of analysis. The average postoperative hospital stay was 11.33 ± 3.27 days. The rate of discharge with good outcomes was 50.0%. Conclusions: Laparoscopic-assisted pancreaticoduodenectomy is a safe alternative to open surgery and represents an appropriate transitional approach toward fully laparoscopic pancreaticoduodenectomy. Keywords: Pancreaticoduodenectomy, Laparoscopy assisted surgery, Ampulla of Vater. References Hank T, Klaiber U, Sahora K, Schindl M, Strobel O. [Surgery for periampullary pancreatic cancer]. Chirurg. 2021;92(9):776-87. Petrova E, Ruckert F, Zach S, Shen Y, Weitz J, Grutzmann R, et al. 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