Antifeedant Activity of Limonoids from the Seeds of Lansium domesticum Corr. Against Subterranean Termite Coptotermes curvignathus

Lansium domesticum is one of Meliaceae plants produces limonoids with various biological activities, except for anti termites. Seven limonoids, dukunolides A-D (DA-DD), F (DF), and langsatides A-B (LA and LB), each previously isolated from the seeds of L. domesticum and prepared at 5 %, together with methanol root extract (MRE) 5 % were evaluated for insecticidal activity against Coptotermes curvignathus. Fifty workers and five soldiers of C. curvignathus were tested in a No-Choice Test to determine which limonoid was the most active. Dukunolides A-D, F, langsatides A-B, and MRE showed weaker antifeedant activity than the regent 50sc (positive standart, 8.04 %), except for dukunolide B (DB) that was stronger antifeedant activity, with a 7.28 % paper weight loss and 33.3 % mortality against C. curvignathus. Conclusion, this study showed limonoid compounds that were isolated from the seeds of L. domesticum could be developed for antitermite drugs.