Evaluation of analgesic and anti-inflammatory activity of ethanolic extract from talinum triangulare on experimental animals

Aim: The study aimed  to evaluate the analgesic and anti- inflammatory activity of ethanolic extract from Talinum Triangulare  on experimental study. Methods:Talinum triangulare plant was extracted with ethanol and the leaves were dried, grind, and extracted with ethanol.The Phytochemical  analysis was conducted  using various test.Albino Wistar rats of either sex weighing (180-200g) and adult male albino mice (25-35g)were used in this study.Talinum Triangulare leaves extract was used to evaluate analgesic activity by acetic acid induced writhing method and anti-inflammatory activity by carrageenan-induced hind paw edema method.The study was conducted with prior approval of Institutional Animal Ethical Committee. Result:In acetic acid induced writhing method,talinum triangulare shows analgesic activity which was statistically significant as compared to control(P<0.05) but less than aceclofenac sodium. In the model of acute inflammation i.e.,carrageenin -induced paw edema in rats , talinum triangulare shows anti -inflammatory activity which was statistically significant as compared to control(P<0.05) but less than indomethacin. Conclusion: The result of this study suggests that the ethanolic extract of talinum triangulare leaves has a potential analgesic and anti-inflammatory activity.