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Hydrazonoyl Chlorides as Precursors for Synthesis of Novel Bis-Pyrrole Derivatives
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A convenient synthesis of some novel bis-pyrrole derivatives via hydrazonoyl halides is described. Antimicrobial evaluation of some selected examples of the synthesized products was carried out. The bis-pyrrole derivative having chloro substituents showed good activity against all of the used microbes. The molecular docking of the bis-pyrrole derivatives was performed by the Molecular Operating Environment (MOE) program.
Title: Hydrazonoyl Chlorides as Precursors for Synthesis of Novel Bis-Pyrrole Derivatives
Description:
A convenient synthesis of some novel bis-pyrrole derivatives via hydrazonoyl halides is described.
Antimicrobial evaluation of some selected examples of the synthesized products was carried out.
The bis-pyrrole derivative having chloro substituents showed good activity against all of the used microbes.
The molecular docking of the bis-pyrrole derivatives was performed by the Molecular Operating Environment (MOE) program.
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