Impact of antibiotic prophylaxis in post-radical cystectomy complications: Should it be enhanced? A systematic review article.

Objective: To evaluate the efficacy and outcome of antibiotic prophylaxis (AP) in patients undergoing radical cystectomy. Study Design: Retrospective Review. Setting: Armed Forces Institute of Urology, Rawalpindi. Period: January 2020 to January 2021. Methods: On patients with bladder cancer undergoing radical cystectomy. Studies were selected irrespective of gender, published in English language in the last five years. PubMed data base is used to review articles. Results: This article attempted to formulate a seat of guidelines through reviews published in various journals regarding AP for post-radical cystectomy patients. Antibiotic prophylaxis is highly recommended for RC since infectious complications accounts for a major complication in postoperative period. The strategy of implementing AP in RC patients could result in the most favorable patient reported outcomes. Conclusion: Our review supports the policy of AP in all patients with bladder cancer undergoing radical cystectomy. Postoperative infections are the modifiable risk factors which can be prevented by antibiotic prophylaxis. Continued efforts are needed to establish an optimal preoperative management plan.