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GenColors: Annotation and comparative genomics made easy
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AbstractGenColors is a web-based software/database system initially aimed at an improved and accelerated annotation of prokaryotic genomes making extensive use of genome comparison (Romualdi et al., Bioinformatics 2005; Romualdi et al., Methods Mol. Biol. 2007). It offers a seamless integration of data from ongoing sequencing projects and annotated genomic sequences obtained from GenBank. With GenColors dedicated genome browsers containing a group of related genomes can be easily set up and maintained. The tool has been efficiently used for sequenceing and annotating the Borrelia garinii genome and is currently applied to a number of other ongoing genome projects on Legionella, Pseudomonas and E. coli genomes. Examples for freely accessible GenColors-based dedicated genome browsers are the Spirochetes Genome Browser SGB ("sgb.fli-leibniz.de":http://sgb.fli-leibniz.de), the Photogenome Browser CGB ("cgb.fli-leibniz.de":http://cgb.fli-leibniz.de) and the Enterobacter Genome Browser ENGENE ("engene.fli-leibniz.de":http://engene.fli-leibniz.de). The system has now been adapted to handle also eukaryotic genomes. A first application of this feature is the annotation and analysis of two fungal species (unpublished). Another GenColors-based tool is the Jena Prokaryotic Genome Viewer - JPGV ("jpgv.fli-leibniz.de":http://jpgv.fli-leibniz.de). Contrary to the dedicated browsers it offers information on almost all finished bacterial genomes. Currently, it includes 1140 genomic elements of 293 species.
Springer Science and Business Media LLC
Title: GenColors: Annotation and comparative genomics made easy
Description:
AbstractGenColors is a web-based software/database system initially aimed at an improved and accelerated annotation of prokaryotic genomes making extensive use of genome comparison (Romualdi et al.
, Bioinformatics 2005; Romualdi et al.
, Methods Mol.
Biol.
2007).
It offers a seamless integration of data from ongoing sequencing projects and annotated genomic sequences obtained from GenBank.
With GenColors dedicated genome browsers containing a group of related genomes can be easily set up and maintained.
The tool has been efficiently used for sequenceing and annotating the Borrelia garinii genome and is currently applied to a number of other ongoing genome projects on Legionella, Pseudomonas and E.
coli genomes.
Examples for freely accessible GenColors-based dedicated genome browsers are the Spirochetes Genome Browser SGB ("sgb.
fli-leibniz.
de":http://sgb.
fli-leibniz.
de), the Photogenome Browser CGB ("cgb.
fli-leibniz.
de":http://cgb.
fli-leibniz.
de) and the Enterobacter Genome Browser ENGENE ("engene.
fli-leibniz.
de":http://engene.
fli-leibniz.
de).
The system has now been adapted to handle also eukaryotic genomes.
A first application of this feature is the annotation and analysis of two fungal species (unpublished).
Another GenColors-based tool is the Jena Prokaryotic Genome Viewer - JPGV ("jpgv.
fli-leibniz.
de":http://jpgv.
fli-leibniz.
de).
Contrary to the dedicated browsers it offers information on almost all finished bacterial genomes.
Currently, it includes 1140 genomic elements of 293 species.
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