Evaluation of the healing process in experimentally induced wounds treated with Aloe vera in sheep

Animal skin trauma can lead to significant tissue loss, requiring specialized treatment for proper healing, Aloe vera, known for its healing properties, has potential benefits for wound treatment in small ruminants. The objective of this study was to evaluate the healing effect of Aloe vera on experimentally induced wounds in sheep. Skin wounds were made in the right and left paralumbar fossa and the animals were subjected to: Negative control group (NC): 1 mL of 0.9% saline solution, Positive control group (PC): 0.1 gram of allopathic ointment based on 35% Lauryl dimethyl benzyl ammonium Chloride and Aloe vera Group (AV): 1g of 10% Aloe vera extract. Topical treatment was carried out in the three experimental groups for 22 days every 24 hours. For macroscopic evaluation, hemorrhage, crust, granulation tissue, swelling, color, hair growth in the area adjacent and epithelialization were evaluated. For microscopic evaluation, morphological aspects such as mononuclear cells and edema epithelialization were evaluated. Macroscopically, it can be inferred that the 10% Aloe vera extract for the treatment of skin wounds in sheep was effective and therefore its use can be suggested as a treatment. In the microscopic analyses, the three groups presented similar results in the evaluation on the 1st, 8th, and 15th day, differing only on the 22nd postoperative day. Therefore, it is concluded that macroscopically and microscopically, Aloe vera 10% presented a satisfactory healing effect, and can be indicated as an alternative in the treatment of skin wounds in sheep.