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Trends in Empirical Treatment of Hospitalized Children with Acute Gastroenteritis in Nigeria
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Background:
Acute gastroenteritis is a common infectious disease
with a high rate of morbidity and mortality in children below five years of age.
Appropriate empirical treatment is therefore vital for reducing the incidence of
the disease.
Objective:
This study aimed at determining the trends in the empirical treatment
of hospitalized children with acute gastroenteritis.
Method:
The study involved the data analysis of 88 medical folders of children
who were diagnosed with gastroenteritis from January to February 2020 (a period
of gastroenteritis yearly outbreak) in Mile 4 Hospital Abakaliki, Ebonyi State,
Nigeria. Socio-demographic data and administered antibiotics data were collected.
Result:
Out of the 88 children, a total of 54 (61%) children were males, while
34 (39%) were females. The ages of the children ranged between 1-51 months,
while the mean age was seen at 14 months. About 58 (66%) were diagnosed with
acute gastroenteritis alone, with children aged 7-12 months recording higher numbers
[25 (28%)]. Severe dehydration was seen as the most common morbidity of
children with acute gastroenteritis. The guardians/parents of these children
stayed at home for an average of 3 days (1-6 days) before visiting the hospital.
The children were treated for an average of 5 days (2-9 days) in the hospital. The
most singly used antibiotics was ciprofloxacin [31 (35%)] followed by a combination
of ciprofloxacin and ceftriaxone [21 (24%)]. About 12 (14%) of the children
were treated using a single dose of the antimalarial drug while 10 (11%)
were treated in double combination therapy. The lowest duration in hospitalization
(4 days) was seen in the use of a single dose regimen, while the highest hospitalization
time (6 days) was seen in the use of a triple dose regimen.
Conclusion:
The best empirical treatment of acute gastroenteritis may involve
the use of ciprofloxacin alone and its combination with ceftriaxone. The severity
of gastroenteritis may also be exacerbated with malaria.
Title: Trends in Empirical Treatment of Hospitalized Children with Acute Gastroenteritis in Nigeria
Description:
Background:
Acute gastroenteritis is a common infectious disease
with a high rate of morbidity and mortality in children below five years of age.
Appropriate empirical treatment is therefore vital for reducing the incidence of
the disease.
Objective:
This study aimed at determining the trends in the empirical treatment
of hospitalized children with acute gastroenteritis.
Method:
The study involved the data analysis of 88 medical folders of children
who were diagnosed with gastroenteritis from January to February 2020 (a period
of gastroenteritis yearly outbreak) in Mile 4 Hospital Abakaliki, Ebonyi State,
Nigeria.
Socio-demographic data and administered antibiotics data were collected.
Result:
Out of the 88 children, a total of 54 (61%) children were males, while
34 (39%) were females.
The ages of the children ranged between 1-51 months,
while the mean age was seen at 14 months.
About 58 (66%) were diagnosed with
acute gastroenteritis alone, with children aged 7-12 months recording higher numbers
[25 (28%)].
Severe dehydration was seen as the most common morbidity of
children with acute gastroenteritis.
The guardians/parents of these children
stayed at home for an average of 3 days (1-6 days) before visiting the hospital.
The children were treated for an average of 5 days (2-9 days) in the hospital.
The
most singly used antibiotics was ciprofloxacin [31 (35%)] followed by a combination
of ciprofloxacin and ceftriaxone [21 (24%)].
About 12 (14%) of the children
were treated using a single dose of the antimalarial drug while 10 (11%)
were treated in double combination therapy.
The lowest duration in hospitalization
(4 days) was seen in the use of a single dose regimen, while the highest hospitalization
time (6 days) was seen in the use of a triple dose regimen.
Conclusion:
The best empirical treatment of acute gastroenteritis may involve
the use of ciprofloxacin alone and its combination with ceftriaxone.
The severity
of gastroenteritis may also be exacerbated with malaria.
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