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Successful Treatment With Minocycline and Saiko-Keishi-to for Covid-19-Associated CNS Lesion
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Neuropsychiatric manifestations of COVID-19 include delirium, general malaise, headache, and psychiatric symptoms. These manifestations are related to the neuroinflammatory response to viral antigens and proinflammatory mediators/immune cells. Tetracyclines, such as minocycline, have antibacterial and anti-inflammatory properties. Saiko-keishi-to, a traditional Japanese Kampo medicine, also has anti-inflammatory properties. Given the anti-inflammatory properties of minocycline and Saiko-keishi-to, we describe two cases of COVID-19 with prolonged headaches and general malaise successfully treated with these medications.
Title: Successful Treatment With Minocycline and Saiko-Keishi-to for Covid-19-Associated CNS Lesion
Description:
Neuropsychiatric manifestations of COVID-19 include delirium, general malaise, headache, and psychiatric symptoms.
These manifestations are related to the neuroinflammatory response to viral antigens and proinflammatory mediators/immune cells.
Tetracyclines, such as minocycline, have antibacterial and anti-inflammatory properties.
Saiko-keishi-to, a traditional Japanese Kampo medicine, also has anti-inflammatory properties.
Given the anti-inflammatory properties of minocycline and Saiko-keishi-to, we describe two cases of COVID-19 with prolonged headaches and general malaise successfully treated with these medications.
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