Anti-cancer and Anti-bacterial Effects of Bioactive Compounds of Scutellaria Species

Background: Cancer has spread rapidly all over the world, and its spread has been considered a big health problem by international organizations. Today, patients prefer to use medicinal plants to treat infectious and non-infectious diseases. Objectives: Considering that Scutellaria has therapeutic properties, this study was conducted to investigate the anti-cancer and anti-bacterial effects of biologically active compounds of Scutellaria species. Materials and Methods: In this research, data were extracted from various research reports and other reliable sources. In this systematic review, websites and databases of Magiran, SID, PubMed, Iranmed, Scopus, and Google scholar were searched for papers published in Persian and English using the keywords of anti-cancer compounds, anti-bacterial, Scutellaria species, and cancer cells. No time limitation was applied. Several interventional studies were identified. These studies were selected based on the purpose of the study. Results: The research results showed that Scutellaria species contain bioactive compounds such as wogonin, wogonoside, baicalein, baicalin, squalane, apigenin, flavonoid, and neobaicalein, which have anti-cancer and anti-microbial properties. Conclusion: Despite the anti-bacterial and anti-cancer properties of Scutellaria species, whether Scutellaria can be used as an anti-cancer and anti-bacterial agent in clinical settings depends on many factors, which need further studies.