Cyberknife-Based Radiosurgery For Glossopharyngeal Neuralgia

Background: Glossopharyngeal Neuralgia (GPN) is a rare and debilitating condition characterized by severe, episodic pain in the distribution of the glossopharyngeal nerve. Traditional treatment options include pharmacological management and invasive surgical procedures, which may not always be effective or suitable for all patients. Stereotactic Radiosurgery (SRS) using the Cyberknife system offers a non-invasive alternative with potential for high precision and efficacy. Objective: This study aims to evaluate the safety and efficacy of Cyberknife-based radiosurgery in the treatment of patients with refractory glossopharyngeal neuralgia. Methods: A retrospective review was conducted on patients diagnosed with glossopharyngeal neuralgia who underwent Cyberknife radiosurgery at our institution. Patient selection criteria included refractory GPN despite medical therapy. Treatment parameters, including target dose and volume, were tailored individually. Outcomes were assessed in terms of pain relief, medication usage, and adverse effects at follow-up intervals. Conclusion: Cyberknife-based radiosurgery appears to be a safe and effective treatment option for patients with refractory glossopharyngeal neuralgia, providing significant pain relief and reducing the need for pharmacological intervention. Further studies with larger sample sizes and longer follow-up periods are warranted to confirm these findings and optimize treatment protocols. Keywords: Glossopharyngeal neuralgia; Cyberknife; Stereotactic radiosurgery; Pain management; Non-invasive treatment