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Chirality Induction in Bioorganometallic Conjugates
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Considerable attention has been given to the research field of bioorganometallic chemistry, which is a hybrid chemistry field between biology and organometallic chemistry. The introduction of biomolecules, which have hydrogen bonding sites and chiral centers, into organometallic compounds is a promising strategy to construct chirality-organized bioorganometallic conjugates. This feature paper sketches an outline of induction of helical chirality into bioorganometallic conjugates by the control of a torsional twist of the organometallic moiety. Topics covered included control of the helical chirality of 1,n′-disubstituted ferrocene moieties in ferrocene-dipeptide conjugates, and the chirality induction of the Au(I)–Au(I) axis in the dinuclear organogold(I)-uracil conjugates.
Title: Chirality Induction in Bioorganometallic Conjugates
Description:
Considerable attention has been given to the research field of bioorganometallic chemistry, which is a hybrid chemistry field between biology and organometallic chemistry.
The introduction of biomolecules, which have hydrogen bonding sites and chiral centers, into organometallic compounds is a promising strategy to construct chirality-organized bioorganometallic conjugates.
This feature paper sketches an outline of induction of helical chirality into bioorganometallic conjugates by the control of a torsional twist of the organometallic moiety.
Topics covered included control of the helical chirality of 1,n′-disubstituted ferrocene moieties in ferrocene-dipeptide conjugates, and the chirality induction of the Au(I)–Au(I) axis in the dinuclear organogold(I)-uracil conjugates.
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