Efficacy of 5% Dextrose+1/2 Saline Versus Ringer Lactate Infusion in Treating Chronic Subdural Hematoma in Terms of Postoperative Pneumocephalus/Subdural Collection after Burr Hole Craniostomy

Objective: To compare the frequency of post-operative pneumocephalus/residual subdural collection after burr hole evacuation of chronic subdural hematoma with 5% dextrose + 1/2 saline infusion versus ringer lactate infusion Subjects and Methods: study was conducted in the Department of Neurosurgery, PIMS, Islamabad from 01-08-2019 to 31-01-2020 .A total of one hundred (n=100) patients of either gender presenting with diagnosis of chronic subdural hematoma, requiring surgical evacuation were included in study and were divided into two groups; Group A given 5% dextrose 1/2 saline intra-op and 1L TDS post-op and Group B given ringer lactate intra-op and 1L TDS post-op. Both groups observed for pneumocephalus and residual subdural collection at 24hr post-op. Results: Results showed that overall frequency of post-op pneumocephalus and subdural collection was significantly lower in patients who were given 5% dextrose+ 12 saline versus ringer lactate group i.e. 14% vs 38% and 4% vs 16 % respectively which was statistically significant with p-value<0.05. Conclusions: There is significant negative correlation with 5% dextrose + 12 saline infusion and post-op pneumocephalus and subdural collection incidence as compared to ringer lactate infusion. KEY WORDS: subdural hematoma, chronic subdural hematoma, burr hole, pneumocephalus, residual subdural, 5% dextrose, ringer lactate.