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Serrated adenoma of stomach: A premalignancy?

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Serrated adenoma is a newly described entity in the group of gastric adenomas. Until date only 20 cases of gastric serrated adenoma have been reported. It is an important entity to be diagnosed accurately as it has a very high-risk of malignant transformation, especially those located in the cardia of stomach. Serrated adenoma associated with adenocarcinoma is more frequent in the elderly, but pure serrated adenoma is common in the young, in whom follow-up is mandatory. Gastric serrated adenoma has distinct location, definite histomorphology and characteristic Ki-67 immunohistochemical staining. Ki-67 staining helps to differentiated pure serrated adenoma from those associated with adenocarcinoma. We present a young adult male, incidentally detected to have gastric serrated adenoma.
Title: Serrated adenoma of stomach: A premalignancy?
Description:
Serrated adenoma is a newly described entity in the group of gastric adenomas.
Until date only 20 cases of gastric serrated adenoma have been reported.
It is an important entity to be diagnosed accurately as it has a very high-risk of malignant transformation, especially those located in the cardia of stomach.
Serrated adenoma associated with adenocarcinoma is more frequent in the elderly, but pure serrated adenoma is common in the young, in whom follow-up is mandatory.
Gastric serrated adenoma has distinct location, definite histomorphology and characteristic Ki-67 immunohistochemical staining.
Ki-67 staining helps to differentiated pure serrated adenoma from those associated with adenocarcinoma.
We present a young adult male, incidentally detected to have gastric serrated adenoma.

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