Search engine for discovering works of Art, research articles, and books related to Art and Culture
ShareThis
Javascript must be enabled to continue!

The Debulking of Recurrent Right Testicular Seminoma with Anterolateral Thigh Flap Reconstruction

View through CrossRef
Introduction: Radical orchidectomy is considered both a therapy and a part of the staging procedure. Stage I seminoma may be treated with orchiectomy alone while the remaining 15% to 20% may have a relapse if they receive no additional treatment during the five-year surveillance. Most recurrences occur within the first 2 years after diagnosis, and the location of the recurrence is typically in the retroperitoneum. This article aims to share the experience in the management of testicular seminoma recurrence in a multidisciplinary approach.Case Presentation: We are reporting a case of a 26-year-old male with a growing mass at the right scrotum just two months after right radical orchidectomy. This patient was previously treated with a stage I seminoma and underwent surveillance. Tumor debulking and right inguinoscrotal reconstruction using a pedicled anterolateral thigh (ALT) flap were done through collaborative surgery between urology and plastic surgery. However, according to National Comprehensive Cancer Network (NCCN), with the relapsed mass, this patient can be classified as having a stage III seminoma and considered as having a good-risk disease due to no evidence of non-pulmonary visceral metastasis. With the risk of bleomycin causing lung fibrosis, four cycles of etoposide and cisplatin can be considered the chemotherapy regimens for this patient. Evaluation after chemotherapy should be done by checking tumor markers and imaging studies.Conclusions: The reappearance of testicular seminoma in this patient unexpectedly occurred quite in a short period, that is in two months after surgery. Immediate multidisciplinary intervention by a urologist and plastic surgeon was done through tumor debulking with a wide incision margin and ALT flap reconstruction. Unfortunately, however, after the second month of follow-up, there was a bulging mass growing beneath the flap which needed further evaluation with ultrasonography to confirm the possibility of tumor recurrence or seroma. If tumor recurrence is confirmed, chemotherapy should be scheduled as soon as possible.
Title: The Debulking of Recurrent Right Testicular Seminoma with Anterolateral Thigh Flap Reconstruction
Description:
Introduction: Radical orchidectomy is considered both a therapy and a part of the staging procedure.
Stage I seminoma may be treated with orchiectomy alone while the remaining 15% to 20% may have a relapse if they receive no additional treatment during the five-year surveillance.
Most recurrences occur within the first 2 years after diagnosis, and the location of the recurrence is typically in the retroperitoneum.
This article aims to share the experience in the management of testicular seminoma recurrence in a multidisciplinary approach.
Case Presentation: We are reporting a case of a 26-year-old male with a growing mass at the right scrotum just two months after right radical orchidectomy.
This patient was previously treated with a stage I seminoma and underwent surveillance.
Tumor debulking and right inguinoscrotal reconstruction using a pedicled anterolateral thigh (ALT) flap were done through collaborative surgery between urology and plastic surgery.
However, according to National Comprehensive Cancer Network (NCCN), with the relapsed mass, this patient can be classified as having a stage III seminoma and considered as having a good-risk disease due to no evidence of non-pulmonary visceral metastasis.
With the risk of bleomycin causing lung fibrosis, four cycles of etoposide and cisplatin can be considered the chemotherapy regimens for this patient.
Evaluation after chemotherapy should be done by checking tumor markers and imaging studies.
Conclusions: The reappearance of testicular seminoma in this patient unexpectedly occurred quite in a short period, that is in two months after surgery.
Immediate multidisciplinary intervention by a urologist and plastic surgeon was done through tumor debulking with a wide incision margin and ALT flap reconstruction.
Unfortunately, however, after the second month of follow-up, there was a bulging mass growing beneath the flap which needed further evaluation with ultrasonography to confirm the possibility of tumor recurrence or seroma.
If tumor recurrence is confirmed, chemotherapy should be scheduled as soon as possible.

Related Results

CDKN2AIP Induces Cellular Senescence and Apoptosis of Testicular Seminoma Tumor by Interacting with CARM1 and eIF4B
CDKN2AIP Induces Cellular Senescence and Apoptosis of Testicular Seminoma Tumor by Interacting with CARM1 and eIF4B
Abstract BackgroundTesticular seminoma are relatively rare tumors, which are mostly detected in male population aged between 15 to 44 years old. Although previous researche...
Clinical Implications of Anterolateral Thigh Flap Shrinkage
Clinical Implications of Anterolateral Thigh Flap Shrinkage
AbstractObjective: To evaluate anterolateral thigh flap shrinkage after elevation and to develop a predictive model for flap design.Method: A prospective study was conducted in a u...
A Safer Way to Harvest a Superthin Perforator Flap
A Safer Way to Harvest a Superthin Perforator Flap
Summary: The updated knowledge of perforasome anatomy and the evolution of microsurgical techniques have enabled surgeons to safely harvest a thin flap. Recently, the a...
Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma
Anaplastic testicular seminoma presenting as a hydrocele, in a 36-year-old patient with a family history of anaplastic seminoma
Testicular cancer is the solid tumor with the greatest incidence in men between 15 and 44 years old. Its main histological type is germ cell tumor, that is divided into seminomatou...
Immunohistochemical comparison between anaplastic seminoma and typical seminoma
Immunohistochemical comparison between anaplastic seminoma and typical seminoma
In order to study the possible biological differences between anaplastic and typical seminoma, the following factors were studied in 11 cases of anaplastic seminoma and 15 cases of...
Anterolateral thigh flap
Anterolateral thigh flap
Abstract The anterolateral thigh (ALT) flap is a versatile soft tissue flap. It can be harvested as a fasciocutaneous or myocutaneous flap. Vascularized fascia ca...
Maternal Smoking During Pregnancy and Risk of Testicular Germ Cell Tumours in Sons
Maternal Smoking During Pregnancy and Risk of Testicular Germ Cell Tumours in Sons
Background: Testicular cancer, predominantly testicular germ cell tumours, is among the most common cancers in young men. Prenatal factors have been suggested to influence disease ...
Oral Cancer and Reconstruction: A Serial Case Report
Oral Cancer and Reconstruction: A Serial Case Report
Introduction : The head and neck cancer are sixth most common cancers worldwide with cancer of oral cavity. The basic treatment modality for the carcinoma of oral cavity has been s...

Back to Top