Case of Unicystic Ameloblastoma with Features of Ameloblastic Fibro-dentinoma

Hybrid odontogenic tumours occur rarely in the oral cavity. The basic histogenesis of these lesions is not clear. Hybrid odontogenic tumours characteristically exhibit two or more distinct morphological features that may lead to a diagnostic dilemma. Unicystic Ameloblastomas (UA) are the second most common odontogenic tumour. Ameloblastic Fibro-dentinoma (AFD) is a rare mixed odontogenic tumour. Both UA and AFD commonly occur in the second decade of life, may be asymptomatic with a slight female predilection, and predominantly occur in the mandibular posterior region. Herein, the authors report a rare case of a 15-year-old female patient complaining of swelling in the right lower posterior jaw region in the last two months. The lesion was surgically enucleated and sent for histopathological examination. On histopathological examination, the lesion exhibits areas of both UA and AFD, representing a rare occurrence of a hybrid odontogenic tumour. The present case report highlights the unique combination of two odontogenic tumours of different origins