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PROTAC GMP Services v1
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BOC Sciences’ GMP production sites were designed in strict accordance to US-FDA guidelines for GMP Manufacturing. It has passed US-FDA inspections. We provide standard QC tests before releasing GMP products. For GMP products, we guarantee >98% purity. In addition, extra tests can be provided according to the requests of clients. Our GMP manufacturing capabilities are designed to meet actual and future customer needs in respect of all stages of PROTAC drug discovery. Advantages Strategic variety encompassed in the combinations of linkers and ligands aids the design of target degraders State-of-the-art techniques and software tools for ligand design and screening Standard QC tests before releasing GMP products Industry-leading turnaround times on deliveries worldwide-and highly competitive pricing Numerous purification options, such as liquid chromatography isolation, silica gel purification, and high-performance liquid chromatography Both research-grade or GMP-grade ligand and linker can be customized. cGMP Manufacturing that is fully traceable
Title: PROTAC GMP Services v1
Description:
BOC Sciences’ GMP production sites were designed in strict accordance to US-FDA guidelines for GMP Manufacturing.
It has passed US-FDA inspections.
We provide standard QC tests before releasing GMP products.
For GMP products, we guarantee >98% purity.
In addition, extra tests can be provided according to the requests of clients.
Our GMP manufacturing capabilities are designed to meet actual and future customer needs in respect of all stages of PROTAC drug discovery.
Advantages Strategic variety encompassed in the combinations of linkers and ligands aids the design of target degraders State-of-the-art techniques and software tools for ligand design and screening Standard QC tests before releasing GMP products Industry-leading turnaround times on deliveries worldwide-and highly competitive pricing Numerous purification options, such as liquid chromatography isolation, silica gel purification, and high-performance liquid chromatography Both research-grade or GMP-grade ligand and linker can be customized.
cGMP Manufacturing that is fully traceable.
Related Results
Interpretable PROTAC degradation prediction with structure-informed deep ternary attention framework
Interpretable PROTAC degradation prediction with structure-informed deep ternary attention framework
Proteolysis Targeting Chimeras (PROTACs) are heterobifunctional ligands that form ternary complexes with Protein Of Interests (POIs) and E3 ligases, exploiting the ubiquitin-protea...
Abstract 1685: Overcoming acquired resistance to PROTAC degraders
Abstract 1685: Overcoming acquired resistance to PROTAC degraders
Abstract
Background: Proteolysis-targeting chimera (PROTAC) technology has been widely investigated for cancer treatment and there have been several PROTAC degrader-...
LM-PROTAC: a language model-driven PROTAC generation pipeline with dual constraints of structure and property
LM-PROTAC: a language model-driven PROTAC generation pipeline with dual constraints of structure and property
Abstract
The imperfect modeling of ternary complexes has limited the application of computer-aided drug discovery tools in PROTAC research and development. In this study, a...
Inner-gMP and gMP-inner inverses
Inner-gMP and gMP-inner inverses
Solving some systems of operator equations, new kinds of generalized inverses are introduced. Since these new inverses can be expressed by inner and gMP inverses, they are called i...
Optogenetic Manipulation of Cyclic Di-GMP (c-di-GMP) Levels Reveals the Role of c-di-GMP in Regulating Aerotaxis Receptor Activity in Azospirillum brasilense
Optogenetic Manipulation of Cyclic Di-GMP (c-di-GMP) Levels Reveals the Role of c-di-GMP in Regulating Aerotaxis Receptor Activity in Azospirillum brasilense
ABSTRACT
Bacterial chemotaxis receptors provide the sensory inputs that inform the direction of navigation in changing environments. Recently, we described t...
Effects of magnesium on cyclic GMP hydrolysis by the bovine retinal rod cyclic GMP phosphodiesterase
Effects of magnesium on cyclic GMP hydrolysis by the bovine retinal rod cyclic GMP phosphodiesterase
Knowledge of the kinetics of the rod cyclic GMP phosphodiesterase is essential for understanding the kinetics and gain of the light response. Therefore, the interactions between Mg...
PROTAC GMP Services v1
PROTAC GMP Services v1
BOC Sciences’ GMP production sites were designed in strict accordance to US-FDA guidelines for GMP Manufacturing. It has passed US-FDA inspections. We provide standard QC tests bef...
Benchmarking of PROTAC docking and virtual screening tools
Benchmarking of PROTAC docking and virtual screening tools
AbstractProteolysis targeting chimeras (PROTACs) are bifunctional compounds that recruit an E3 ligase to a target protein to induce ubiquitination and degradation of the target and...