Unraveling the antifungal, antibacterial activity, and cytotoxicity analysis of Ziziphus oenoplia

Modern biomedical sciences are developing research in the field of antibacterial medications. The Indian traditional medical system of Ayurveda is being studied by researchers who are working to create new medications from natural resources. The majority of these medications have plant origins. This study studied the antifungal and antibacterial activity, along with the cytotoxicity of Ziziphus oenoplia. The fined powder of Ziziphus oenoplia was used, and a well diffusion assay was used to assess the antifungal and antibacterial activity. Finally, the cytotoxicity of the plant extract was also analyzed by using a cell line. The outcomes indicate that the bark, leaf, and fruit extract shows potent antibacterial as well as antifungal properties. The highest zone of inhibition observed against E. coli was shown by the fruit extract (20.66 mm). Furthermore, the cytotoxicity assay on the SW480 cell line demonstrated that the extracts are either minimally toxic or non-toxic. However, dose-dependent cytotoxicity has been seen in vitro. Although green synthesis has grown more popular due to its environmentally friendly processes, further clinical trials are required.