Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Significance of Cellular Lipid Metabolism for the Replication of Rotaviruses and Other RNA Viruses
View through CrossRef
The replication of species A rotaviruses (RVAs) involves the recruitment of and interaction with cellular organelles’ lipid droplets (LDs), both physically and functionally. The inhibition of enzymes involved in the cellular fatty acid biosynthesis pathway or the inhibition of cellular lipases that degrade LDs was found to reduce the functions of ‘viral factories’ (viroplasms for rotaviruses or replication compartments of other RNA viruses) and decrease the production of infectious progeny viruses. While many other RNA viruses utilize cellular lipids for their replication, their detailed analysis is far beyond this review; only a few annotations are made relating to hepatitis C virus (HCV), enteroviruses, SARS-CoV-2, and HIV-1.
Title: Significance of Cellular Lipid Metabolism for the Replication of Rotaviruses and Other RNA Viruses
Description:
The replication of species A rotaviruses (RVAs) involves the recruitment of and interaction with cellular organelles’ lipid droplets (LDs), both physically and functionally.
The inhibition of enzymes involved in the cellular fatty acid biosynthesis pathway or the inhibition of cellular lipases that degrade LDs was found to reduce the functions of ‘viral factories’ (viroplasms for rotaviruses or replication compartments of other RNA viruses) and decrease the production of infectious progeny viruses.
While many other RNA viruses utilize cellular lipids for their replication, their detailed analysis is far beyond this review; only a few annotations are made relating to hepatitis C virus (HCV), enteroviruses, SARS-CoV-2, and HIV-1.
Related Results
Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis
Hepatitis C Virus Replication Depends on Endosomal Cholesterol Homeostasis
ABSTRACT
Similar to other positive-strand RNA viruses, hepatitis C virus (HCV) causes massive rearrangements of intracellular membranes, resulting in a membranous web (MW...
Detecting RNA–RNA interactome
Detecting RNA–RNA interactome
AbstractThe last decade has seen a robust increase in various types of novel RNA molecules and their complexity in gene regulation. RNA molecules play a critical role in cellular e...
Capsid‐Less
RNA
Viruses
Capsid‐Less
RNA
Viruses
Abstract
Capsid‐less RNA viruses comprise an assemblage of diverse virus‐like agents with genomes of variable size that share onl...
Biophysical studies of RNA:DNA:DNA triplexes and characterization of riboswitches in cell-free transcription-translation systems
Biophysical studies of RNA:DNA:DNA triplexes and characterization of riboswitches in cell-free transcription-translation systems
RNA research is very important since RNA molecules are involved in various gene regulatory mechanisms as well as pathways of cell physiology and disease development.1 RNAs have evo...
Revealing RNA virus diversity and evolution in unicellular algae transcriptomes
Revealing RNA virus diversity and evolution in unicellular algae transcriptomes
Abstract
Remarkably little is known about the diversity and evolution of RNA viruses in unicellular eukaryotes. We screened a total of 570 transcriptomes from the...
Review dari Metabolisme Karbohidrat, Lipid, Protein, dan Asam Nukleat
Review dari Metabolisme Karbohidrat, Lipid, Protein, dan Asam Nukleat
Artikel review ini mengulas tentang prinsip dan proses metabolisme karbohidrat, lipid, protein dan asam nukeat pada organisme. Telaah pustaka yang disajikan dalam review ini bersu...
B-247 BLADE-R: streamlined RNA extraction for clinical diagnostics and high-throughput applications
B-247 BLADE-R: streamlined RNA extraction for clinical diagnostics and high-throughput applications
Abstract
Background
Efficient nucleic acid extraction and purification are crucial for cellular and molecular biology research, ...
Phylogenomic analysis of Uganda influenza type-A viruses to assess their relatedness to the vaccine strains and other Africa viruses: a molecular epidemiology study
Phylogenomic analysis of Uganda influenza type-A viruses to assess their relatedness to the vaccine strains and other Africa viruses: a molecular epidemiology study
ABSTRACT
Background
Genetic characterisation of circulating influenza viruses is essential for vaccine selection and mitigation...