Biosynthesized Silver Nanoparticles Generated from Eucalyptus camaldulensis Show Synergistic Efficacy Against Multidrug-resistant Bacteria

Background: The use of plant extracts as both reducing and capping agents in the biosynthesis of silver nanoparticles (AgNPs) has a wide range of potential applications in addressing diverse biological challenges. Objectives: The objective of this research was to broaden the scope of AgNPs by the use of a new phytochemical approach characterized by low toxicity and production cost objective: The objective of this research was to broaden the scope of AgNPs by the use of a new phytochemical approach characterised by low toxicity and production cost. This method included the manufacture of nanoparticles using aqueous leaf extracts derived from Eucalyptus camaldulensis. Method: This method included the manufacture of nanoparticles using aqueous leaf extracts derived from Eucalyptus camaldulensis. Results: The biosynthesis of AgNPs was subjected to characterization using many analytical techniques. The findings from the transmission electron microscopy (TEM) analysis revealed the presence of mostly spherical-shaped silver nanoparticles (AgNPs). The size distribution of these AgNPs was shown to be influenced by the kind of plant leaf extract used. Specifically, AgNPs derived from E. camaldulensis extract exhibited lower sizes, ranging from 16 nm to 22 nm. Conclusion: Silver nanoparticles (AgNPs) exhibit significantly enhanced antibacterial efficacy against a wide range of Gram-positive and Gram-negative bacterial strains, surpassing the potency of the plant extracts used in their production.