Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Heavy Metal and Antibiotic Co-resistance in Bacteria Isolated from Poultry Samples in Bangladesh: An Emerging Environmental Threat
View through CrossRef
Abstract
The excessive use of heavy metals and antibiotics as additives in livestock feed may significantly contribute to bacterial resistance in poultry environments by exerting selective pressure. This study aimed to comprehensively analyze bacterial isolates from poultry farms across Bangladesh, focusing on their resistance to heavy metals and antibiotics. Through microbial phenotypic screening, 23 cadmium-resistant and 28 chromium-resistant bacterial isolates were identified. The minimum inhibitory concentrations (MICs) for cadmium and chromium in metal-resistant bacterial isolates varied significantly, ranging from 200 μg/ml to 1600 μg/ml. All cadmium-resistant isolates were fully resistant to cefixime and ceftazidime, while chromium-resistant isolates showed 90% resistance to tetracycline. The cadmium resistance gene, such as
czc
, was detected in 26% (6/23) of cadmium-resistant isolates, and the chromium reductase gene
chrR
was detected in 18% (5/28) of chromium-resistant isolates. Among the chromium-reductase isolates, 40% (2/5) exhibited co-resistance and harbored the
chrR
gene, beta-lactam resistance genes (
bla-TEM
,
bla-NDM
), and the colistin resistance gene (
mcr-2
). A significant association (p = 0.026) was observed between the presence of the
chrR
gene and these antibiotic resistance genes. However, no co-resistance was found in cadmium-resistant isolates. Mobile genetic elements, specifically Class 1 integrons, were found in 33.33% (2/6) of the isolates carrying the cadmium resistance gene (
czc
) and in 100% (5/5) of the isolates containing the chromium reductase gene (
chrR
). These findings underscore poultry environments in Bangladesh as significant reservoirs for bacteria with dual resistance to heavy metals and antibiotics, emphasizing the need for further investigation into the genetic mechanisms driving microbial resistance and its implications for public health.
Title: Heavy Metal and Antibiotic Co-resistance in Bacteria Isolated from Poultry Samples in Bangladesh: An Emerging Environmental Threat
Description:
Abstract
The excessive use of heavy metals and antibiotics as additives in livestock feed may significantly contribute to bacterial resistance in poultry environments by exerting selective pressure.
This study aimed to comprehensively analyze bacterial isolates from poultry farms across Bangladesh, focusing on their resistance to heavy metals and antibiotics.
Through microbial phenotypic screening, 23 cadmium-resistant and 28 chromium-resistant bacterial isolates were identified.
The minimum inhibitory concentrations (MICs) for cadmium and chromium in metal-resistant bacterial isolates varied significantly, ranging from 200 μg/ml to 1600 μg/ml.
All cadmium-resistant isolates were fully resistant to cefixime and ceftazidime, while chromium-resistant isolates showed 90% resistance to tetracycline.
The cadmium resistance gene, such as
czc
, was detected in 26% (6/23) of cadmium-resistant isolates, and the chromium reductase gene
chrR
was detected in 18% (5/28) of chromium-resistant isolates.
Among the chromium-reductase isolates, 40% (2/5) exhibited co-resistance and harbored the
chrR
gene, beta-lactam resistance genes (
bla-TEM
,
bla-NDM
), and the colistin resistance gene (
mcr-2
).
A significant association (p = 0.
026) was observed between the presence of the
chrR
gene and these antibiotic resistance genes.
However, no co-resistance was found in cadmium-resistant isolates.
Mobile genetic elements, specifically Class 1 integrons, were found in 33.
33% (2/6) of the isolates carrying the cadmium resistance gene (
czc
) and in 100% (5/5) of the isolates containing the chromium reductase gene (
chrR
).
These findings underscore poultry environments in Bangladesh as significant reservoirs for bacteria with dual resistance to heavy metals and antibiotics, emphasizing the need for further investigation into the genetic mechanisms driving microbial resistance and its implications for public health.
Related Results
Evolution of Antimicrobial Resistance in Community vs. Hospital-Acquired Infections
Evolution of Antimicrobial Resistance in Community vs. Hospital-Acquired Infections
Abstract
Introduction
Hospitals are high-risk environments for infections. Despite the global recognition of these pathogens, few studies compare microorganisms from community-acqu...
A Review on the Synergistic Approaches for Heavy Metals Bioremediation: Harnessing the Power of Plant-Microbe Interactions
A Review on the Synergistic Approaches for Heavy Metals Bioremediation: Harnessing the Power of Plant-Microbe Interactions
Heavy metals contamination is a serious threat to all life forms. Long term exposure of heavy metals can lead to different life-threatening medical conditions including cancers of ...
ISOLATION IDENTIFICATION AND CHARACTERIZATION OF SALMONELLA SPP. FROM POULTRY AND POULTRY PRODUCT IN KHARTOUM STATE- SUDAN
ISOLATION IDENTIFICATION AND CHARACTERIZATION OF SALMONELLA SPP. FROM POULTRY AND POULTRY PRODUCT IN KHARTOUM STATE- SUDAN
Salmonella, a genus of the family Enterobacteriaceae with over 2450 species, has been responsible for diseases ranging from typhoidal
salmonellosis to non- typhoidal salmonellosis....
Phenotypic and Molecular Characterization of the blaTEM Gene in Extended-Spectrum Beta-Lactamase-Producing Klebsiella pneumoniae
Phenotypic and Molecular Characterization of the blaTEM Gene in Extended-Spectrum Beta-Lactamase-Producing Klebsiella pneumoniae
Abstract
Introduction
There has been a notable rise in antibiotic resistance among enterobacteria. This issue is primarily attributed to the emergence of extended-spectrum beta-lac...
Isolation And Characterization Of Biosurfactant Producing Bacteria From Different Environmental Soil Samples
Isolation And Characterization Of Biosurfactant Producing Bacteria From Different Environmental Soil Samples
Biosurfactants are natural substances produced by several bacterial and fungal organisms that are amphiphilic and are extracellular (a part of the cell membrane). Biosurfactants ca...
Occurrence, Risk factors and Antimicrobial resistance of
Campylobacter
from Poultry and Humans in Central Ethiopia: A One Health Approach
Occurrence, Risk factors and Antimicrobial resistance of
Campylobacter
from Poultry and Humans in Central Ethiopia: A One Health Approach
Abstract
Background
Campylobacter
is a leading foodborne pathogen posing a significant...
Assessment of poultry rearing practices and risk factors of H5N1 and H9N2 virus circulating among backyard chickens and ducks in rural communities
Assessment of poultry rearing practices and risk factors of H5N1 and H9N2 virus circulating among backyard chickens and ducks in rural communities
Background
The avian influenza virus (AIV) causes significant economic losses by infecting poultry and occasional spillover to humans. Backyard farms are vulnerable to AIV epidemic...
Effect of Gram-positive bacteria on antibiotic resistance in Gram-negative bacteria
Effect of Gram-positive bacteria on antibiotic resistance in Gram-negative bacteria
Antibiotics are one of the most common treatments for bacterial infections, but the emergence of antibiotic resistance is a major threat to the control of infectious diseases. Many...