Javascript must be enabled to continue!
CAR-T-Zell-Therapie ökonomisch vertretbar
View through CrossRef
Die CAR-T-Zell-Therapie kommt als Drittlinientherapie diffus großzelliger B-Zell-Lymphome (DLBCL) in Betracht. Allein die einmalige Infusion der Hauptprotagonisten Axicapatagen Ciloleucel und Tisagenlecleucel werde in Deutschland mit 282 000 und 275 000 Euro erstattet, so die deutsche Studiengruppe um Skalt D. Die Budget-Impact-Analyse (BIA) zeige aber, dass die Kosten verglichen mit anderen Behandlungen durchaus vertretbar sind.
Title: CAR-T-Zell-Therapie ökonomisch vertretbar
Description:
Die CAR-T-Zell-Therapie kommt als Drittlinientherapie diffus großzelliger B-Zell-Lymphome (DLBCL) in Betracht.
Allein die einmalige Infusion der Hauptprotagonisten Axicapatagen Ciloleucel und Tisagenlecleucel werde in Deutschland mit 282 000 und 275 000 Euro erstattet, so die deutsche Studiengruppe um Skalt D.
Die Budget-Impact-Analyse (BIA) zeige aber, dass die Kosten verglichen mit anderen Behandlungen durchaus vertretbar sind.
Related Results
Functional Diversification and Dynamics of CAR-T Cells in B-ALL Patients
Functional Diversification and Dynamics of CAR-T Cells in B-ALL Patients
Chimeric antigen receptor-engineered (CAR)-T cell therapy represents one of the most promising strategies of cancer treatment, and the function and persistence of CAR-T cells in vi...
Selinexor Reduces the Immunosuppressive Properties of Macrophages and Synergizes with CD19 CAR-T Cells Against B-Cell Lymphoma
Selinexor Reduces the Immunosuppressive Properties of Macrophages and Synergizes with CD19 CAR-T Cells Against B-Cell Lymphoma
Background: CD19 chimeric antigen receptor (CAR)-T cell therapy has achieved high response rates in patients with B-cell lymphoma (BCL). However, treatment failure and relapse can ...
Combinatorial Antigen Targeting Strategy for Acute Myeloid Leukemia
Combinatorial Antigen Targeting Strategy for Acute Myeloid Leukemia
Introduction: Efforts to safely and effectively treat acute myeloid leukemia (AML) by targeting a single leukemia associated antigen with chimeric antigen receptor T (CAR T) cells ...
CAR-macrophages targets CD26 to eliminate chronic myeloid leukemia stem cells
CAR-macrophages targets CD26 to eliminate chronic myeloid leukemia stem cells
Abstract
Background
Chronic myeloid leukemia stem cells (CML-LSCs), which exhibit resistance to tyrosine kinase inhibitors (TKIs), are the leadin...
Risk Factors and Characteristics of CRS in CAR-T Treatment
Risk Factors and Characteristics of CRS in CAR-T Treatment
Background and objective
Clinical trials have confirmed that CAR-T treatment has become one of the important treatments for many relapse and refractory hematological...
Abstract 1490: Dual chlorotoxin and methylguanine methyltransferase γδ-T cells for drug resistant immunotherapy of glioblastoma multiforme
Abstract 1490: Dual chlorotoxin and methylguanine methyltransferase γδ-T cells for drug resistant immunotherapy of glioblastoma multiforme
Abstract
While recent advances in immunotherapies have shown promise in extracranial tumors, Glioblastoma Multiforme (GBM) has remained impervious to these advances ...
Abstract 1782: Functional potency assay predicts CAR-T effectiveness in tumor microenvironment
Abstract 1782: Functional potency assay predicts CAR-T effectiveness in tumor microenvironment
Abstract
Chimeric antigen receptor (CAR) T cell therapy holds great promise for the treatment of various cancers, including solid tumors. However, attempts to model ...
Allelische Subtypisierung und Funktionsanalyse von inhibitorischen NK-Zell-Rezeptoren KIR2DL1 und KIR3DL1 zur Optimierung der Spenderauswahl bei NK-Zell-basierter Immuntherapie
Allelische Subtypisierung und Funktionsanalyse von inhibitorischen NK-Zell-Rezeptoren KIR2DL1 und KIR3DL1 zur Optimierung der Spenderauswahl bei NK-Zell-basierter Immuntherapie
In Deutschland erkranken pro Jahr bis zu 12.000 Menschen neu an Leukämie. Leukämie ist eine schwere onkologische Erkrankung, bei der reifes Knochenmarkgewebe in Folge von Mutatione...

