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Effect of Murraya Exotica Methanol Extract Activities on Human Blood Clotting Time
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Murraya exotica (Tilson) Rutaceae has been shown ethno-medicinally to have anti-inflammatory, antinociceptive and insecticidal activities. The effect of the methanol extract of M. exotica leaves was investigated using a modified method of Lee and White assay for blood clotting in vitro. There was significant decrease (p˂0.05) in human blood clotting time (6.161.883 min) in samples treated with 0.006 g of the M. exotica compared to the control clotting time (7.821.279 min). Also 0.036 g of the M. exotica significantly (p ˂0.05) increased human blood clotting time (10.891.276 min) compared to control while the blood samples treated with 0.012 g and 0.024 g of plant extract showed no significant difference in the human blood clotting time. M. exotica plant extract have a biphasic effect on the human blood clotting time.
International Academic and Research Consortium
Title: Effect of Murraya Exotica Methanol Extract Activities on Human Blood Clotting Time
Description:
Murraya exotica (Tilson) Rutaceae has been shown ethno-medicinally to have anti-inflammatory, antinociceptive and insecticidal activities.
The effect of the methanol extract of M.
exotica leaves was investigated using a modified method of Lee and White assay for blood clotting in vitro.
There was significant decrease (p˂0.
05) in human blood clotting time (6.
161.
883 min) in samples treated with 0.
006 g of the M.
exotica compared to the control clotting time (7.
821.
279 min).
Also 0.
036 g of the M.
exotica significantly (p ˂0.
05) increased human blood clotting time (10.
891.
276 min) compared to control while the blood samples treated with 0.
012 g and 0.
024 g of plant extract showed no significant difference in the human blood clotting time.
M.
exotica plant extract have a biphasic effect on the human blood clotting time.
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