Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Effects of Three Anesthesia Methods on Inflammation, Oxidative Stress, Analgesia and Cognition in Elderly Patients Receiving Hip Replacement
View through CrossRef
The study aimed to investigate the effects of different anesthesia methods on the analgesia,
inflammation and oxidative stress levels and cognitive function in elderly patients undergoing hip
replacement. 100 elderly patients requiring hip replacement and admitted to Tianjin Hospital from
March 2017 to March 2019 were enrolled and divided into group A (n=35, general anesthesia with
endotracheal intubation), group B (n=35, epidural anesthesia) and group C (n=30, general anesthesia
with endotracheal intubation + epidural anesthesia). The basic vital signs, inflammatory factors, stress
response indicators and cognitive function changes were compared among three groups. Additionally,
the effects of three different anesthesia methods were analyzed based on the differences in postoperative
analgesic effect, extubation time and recovery time. The vital signs [systolic blood pressure (SBP),
diastolic blood pressure (DBP) and heart rate (HR)] were lower in group C than those in group A and
group B after surgery (p<0.05). The VAS score at 12 h and 24 h after surgery was lower than that at 3 h
after surgery (p<0.05). Group A and B had increased levels of these inflammatory factors after surgery
compared with those before surgery. Postoperative extubation time, eye-opening time upon calling and
recovery time were significantly shorter in group C than those in groups A and B (p<0.05). The
oxidative stress indexes in group C were remarkably lower than those in groups A and B (p<0.05). The
MMSE score was decreased in groups A and B after surgery compared with that before surgery
(p<0.05). General anesthesia combined with epidural anesthesia applied in elderly patients undergoing
hip replacement achieves a good anesthetic effect and is able to stabilize the vital signs and stress levels
of patients and improve postoperative analgesic effect and cognitive function, which is worthy of
popularization in clinical practice.
CMB Association
Title: Effects of Three Anesthesia Methods on Inflammation, Oxidative Stress, Analgesia
and Cognition in Elderly Patients Receiving Hip Replacement
Description:
The study aimed to investigate the effects of different anesthesia methods on the analgesia,
inflammation and oxidative stress levels and cognitive function in elderly patients undergoing hip
replacement.
100 elderly patients requiring hip replacement and admitted to Tianjin Hospital from
March 2017 to March 2019 were enrolled and divided into group A (n=35, general anesthesia with
endotracheal intubation), group B (n=35, epidural anesthesia) and group C (n=30, general anesthesia
with endotracheal intubation + epidural anesthesia).
The basic vital signs, inflammatory factors, stress
response indicators and cognitive function changes were compared among three groups.
Additionally,
the effects of three different anesthesia methods were analyzed based on the differences in postoperative
analgesic effect, extubation time and recovery time.
The vital signs [systolic blood pressure (SBP),
diastolic blood pressure (DBP) and heart rate (HR)] were lower in group C than those in group A and
group B after surgery (p<0.
05).
The VAS score at 12 h and 24 h after surgery was lower than that at 3 h
after surgery (p<0.
05).
Group A and B had increased levels of these inflammatory factors after surgery
compared with those before surgery.
Postoperative extubation time, eye-opening time upon calling and
recovery time were significantly shorter in group C than those in groups A and B (p<0.
05).
The
oxidative stress indexes in group C were remarkably lower than those in groups A and B (p<0.
05).
The
MMSE score was decreased in groups A and B after surgery compared with that before surgery
(p<0.
05).
General anesthesia combined with epidural anesthesia applied in elderly patients undergoing
hip replacement achieves a good anesthetic effect and is able to stabilize the vital signs and stress levels
of patients and improve postoperative analgesic effect and cognitive function, which is worthy of
popularization in clinical practice.
Related Results
Mix En Meng It Op: Emile YX?'s Alternative Race and Language Politics in South African Hip-Hop
Mix En Meng It Op: Emile YX?'s Alternative Race and Language Politics in South African Hip-Hop
This paper explores South African hip-hop activist Emile YX?'s work to suggest that he presents an alternative take on mainstream US and South African hip-hop. While it is arguable...
The Practice of Multimodal Analgesia Technique for Patients Undergoing Surgery under General Anaesthesia in Debre Markos Compersive Specialized Hospital Debre Markos, East Gojjam, Ethiopia, 2022. A Cross-Sectional Study
The Practice of Multimodal Analgesia Technique for Patients Undergoing Surgery under General Anaesthesia in Debre Markos Compersive Specialized Hospital Debre Markos, East Gojjam, Ethiopia, 2022. A Cross-Sectional Study
Background: Practice guidelines for preoperative pain management recommend that multimodal analgesic therapy should be used for postsurgical patients. This method uses different a...
DXA-derived hip shape is associated with hip fracture: a longitudinal study of 38,123 UK Biobank participants
DXA-derived hip shape is associated with hip fracture: a longitudinal study of 38,123 UK Biobank participants
Abstract
Despite advancements in fracture prediction tools and osteoporosis management, hip fractures remain a significant consequence of bone fragility, with a 22% one...
S68. DIFFERENTIAL PATTERN OF SOCIAL COGNITION IMPAIRMENT BETWEEN RURAL AND URBAN DWELLING PATIENTS OF SCHIZOPHRENIA AND ITS FUNCTIONAL CORRELATES
S68. DIFFERENTIAL PATTERN OF SOCIAL COGNITION IMPAIRMENT BETWEEN RURAL AND URBAN DWELLING PATIENTS OF SCHIZOPHRENIA AND ITS FUNCTIONAL CORRELATES
Abstract
Background
Cognitive deficits (both neuro & social Cognition) play a vital role in determining functional status in...
20 Does hip involvement affect foot and ankle in juvenile idiopathic arthritis?
20 Does hip involvement affect foot and ankle in juvenile idiopathic arthritis?
Abstract
Background
Although ankle and foot involvements are common in juvenile idiopathic arthritis (JIA), they are often negle...
INCIDENCE OF POST DURAL PUNCTURE HEADACHE: A COMPARATIVE ANALYSIS BETWEEN MEDIAN VERSUS PARAMEDIAN APPROACH TO SUB-ARACHNOID SPACE IN PATIENTS UNDERGOING ELECTIVE CESAREAN SECTION
INCIDENCE OF POST DURAL PUNCTURE HEADACHE: A COMPARATIVE ANALYSIS BETWEEN MEDIAN VERSUS PARAMEDIAN APPROACH TO SUB-ARACHNOID SPACE IN PATIENTS UNDERGOING ELECTIVE CESAREAN SECTION
Background: Post dural puncture headache is the common complication after spinal anesthesia due to puncture of dura matter. This complication is frequent in Obstetric patients who ...
Nursing Methods and Experience of Local Anesthesia Patients under Arthroscope
Nursing Methods and Experience of Local Anesthesia Patients under Arthroscope
In order to solve the nursing problems of local anesthesia patients under arthroscopy, a nursing method and experience based on local anesthesia patients under arthroscopy was prop...
Vertebral fractures as a precursor to potential hip fractures in elderly women
Vertebral fractures as a precursor to potential hip fractures in elderly women
Abstract
Objective: The purpose of this study was to investigate the kind of low-energy fracture which is a precursor of hip fracture in the elderly, and to suggest the imp...