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Supplementary Figure 1 from Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21
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Supplementary Figure 1 from Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21
American Association for Cancer Research (AACR)
Title: Supplementary Figure 1 from Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21
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Supplementary Figure 1 from Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21.
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Data from Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21
Data from Histone Deacetylase Inhibitors Induce Cell Death Selectively in Cells That Harbor Activated kRasV12: The Role of Signal Transducers and Activators of Transcription 1 and p21
<div>Abstract<p>Histone deacetylase (HDAC) inhibitors (HDACi) show potent and selective antitumor activity despite the fact that they induce histone hyperacetylation in...
Complex Collision Tumors: A Systematic Review
Complex Collision Tumors: A Systematic Review
Abstract
Introduction: A collision tumor consists of two distinct neoplastic components located within the same organ, separated by stromal tissue, without histological intermixing...
Cell-cycle-dependent repression of histone gene transcription by histone H4
Cell-cycle-dependent repression of histone gene transcription by histone H4
Abstract
In all eukaryotes DNA replication is coupled to histone synthesis to coordinate chromatin packaging of the genome. Canonical histone gen...
Blockade of histone deacetylase activity affects transcription and splicing of neuronal and glial genes
Blockade of histone deacetylase activity affects transcription and splicing of neuronal and glial genes
The study of the molecular mechanisms underlying plastic processes in the nervous system is of great interest in modern neuroscience. It is important to understand that epigenetic ...
Abstract 1071: DeltaEF1 promotes breast cancer cell proliferation through down-regulating p21 expression
Abstract 1071: DeltaEF1 promotes breast cancer cell proliferation through down-regulating p21 expression
Abstract
Background: Deregulation of the cell cycle and abnormal cell proliferation are involved in breast carcinogenesis. Recent evidence suggests that deltaEF1, a ...
Abstract 1840: Clinical significance of lincRNA-p21 in colorectal cancer.
Abstract 1840: Clinical significance of lincRNA-p21 in colorectal cancer.
Abstract
Large Intergenic Noncoding RNAs (LincRNAs) have been recently shown to be novel regulators for both transcription and posttranscriptional/translation. One o...
Successful transfection of Lymphoblastoid cell line (Preprint)
Successful transfection of Lymphoblastoid cell line (Preprint)
BACKGROUND
Immortalization is the stage that the cell goes through before full transformation [1]. Human resting B lymphocytes from peripheral blood are eas...
Abstract A212: Preclinical efficacy of MEK inhibition in a K-Ras driven cholangiocarcinoma preclinical model
Abstract A212: Preclinical efficacy of MEK inhibition in a K-Ras driven cholangiocarcinoma preclinical model
Abstract
Intrahepatic cholangiocarcinoma (iCCA) is a form of deadly malignancy with limited treatment options. Gain-of-function mutations in KRAS are one of the most...