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Response to ‘A spectrum of BAP1 expression from naevus to melanoma in a patient with BAP1 tumour predisposition syndrome’
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A recent paper described a spectrum of BAP1 expression ranging from naevus to melanoma in a patient with BAP1 tumour predisposition syndrome, who subsequently developed liver metastases and died. We present two similar sporadic cases in which patients with BAP1-inactivated melanocytomas (BIMs) developed visceral metastases. Our patients provide further evidence that not all BIMs run an indolent course.
Oxford University Press (OUP)
Title: Response to ‘A spectrum of BAP1 expression from naevus to melanoma in a patient with BAP1 tumour predisposition syndrome’
Description:
A recent paper described a spectrum of BAP1 expression ranging from naevus to melanoma in a patient with BAP1 tumour predisposition syndrome, who subsequently developed liver metastases and died.
We present two similar sporadic cases in which patients with BAP1-inactivated melanocytomas (BIMs) developed visceral metastases.
Our patients provide further evidence that not all BIMs run an indolent course.
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