Sero-prevalence of hepatitis viral infections among sanitary workers Across the Worldwide: Meta-Analysis and Systematic Review

Abstract Background: Sanitary workers are the possibility of have hepatitis viral infections due their working conditions. Thus, the aim of the review was to estimate the pooled sero-prevalence occupational related hepatitis viral infection among sanitary workers across the world. Methods: PRISMA and PICOS were used flow diagram and review questions, respectively. Four databases other methods were used published articles from 2000 to 2022. Boolean logic (AND, OR), MeSH, and keywords were used: (Occupation *OR Job *OR Work) AND (Hepatitis Infection A *OR B *OR C *OR E) AND (Solid waste collectors [SWCs] *OR Street sweepers [SS] *OR Sewage workers [STW] *OR health facilities cleaners [HCFC) AND (Countries). CMA software used for data analysis (95%CI) Results: A total of 178 studies were identified studies, a total of 25 studies were included from eleven countries. Of these, from developed (n=7 ) and developing countries (n=4). From total of sanitary workers (N= 7,945), 5951(74%), 1609 (21%) and 385 (5%) were STW, SWCs and SS, respectively. The overall pooled Sero-prevalence of HAV infection among sanitary workers across the world was 56.7% (95%CI: 0.44-0.69; p-value =0.32). While, 22.6% (95%CI: 0.10-0.44; p-value=0.01), 22.8% (95%CI: 0.10-0.45; p-value=0.02) and 33.1% (95%CI: 0.18-0.54; p-value=0.10) for HBV, HCV and HEV, respectively Conclusion: The current pooled prevalence concluded that sanitary workers are at the risk of occupational related hepatitis viral infections that need governmental policies amendment and other efforts to mitigate these risks.