Search engine for discovering works of Art, research articles, and books related to Art and Culture
ShareThis
Javascript must be enabled to continue!

The platelet aIIbβIII integrin has no role in thrombosis in myeloproliferative neoplasm

View through CrossRef
We present a patient with congenital Glanzmann Thrombasthenia, who developed recurrent venous thrombosis. Over time, she developed the clinical picture of a myeloproliferative neoplasm, being JAK2 positive. This case clearly indicates that the platelet aIIbβIII integrin (lacking in Glanzmann thrombasthenia) does not have a role in thrombosis in MPN
Title: The platelet aIIbβIII integrin has no role in thrombosis in myeloproliferative neoplasm
Description:
We present a patient with congenital Glanzmann Thrombasthenia, who developed recurrent venous thrombosis.
Over time, she developed the clinical picture of a myeloproliferative neoplasm, being JAK2 positive.
This case clearly indicates that the platelet aIIbβIII integrin (lacking in Glanzmann thrombasthenia) does not have a role in thrombosis in MPN.

Related Results

PATHOPHYSIOLOGY OF THROMBOCYTOPENIA AND RESULTANT CLINICAL INDICATIONS FOR PLATELET TRANSFUSION
PATHOPHYSIOLOGY OF THROMBOCYTOPENIA AND RESULTANT CLINICAL INDICATIONS FOR PLATELET TRANSFUSION
Careful evaluation of platelet survival data in normal individuals and patients with thrombocytopeniasecondary to marrow aplasia has demonstrated that platelets are lost from circu...
The Prevalence of JAK2 Mutation in High-Altitude Patients with Unprovoked Thrombosis and Thrombosis at Unusual Sites
The Prevalence of JAK2 Mutation in High-Altitude Patients with Unprovoked Thrombosis and Thrombosis at Unusual Sites
Introduction Thrombosis, both arterial and venous, is a major source of morbidity and mortality in patients with myeloproliferative neoplasms (MPNs). Thrombosis can ...
Abstract 3900: Alpha2beta1 integrin regulation of endothelial notch signaling in the retina.
Abstract 3900: Alpha2beta1 integrin regulation of endothelial notch signaling in the retina.
Abstract Angiogenesis expands the vascular network during normal development and in response to angiogenic stress. Dysregulation of this dynamic process contributes ...
Kindlin Assists Talin to Promote Integrin Activation
Kindlin Assists Talin to Promote Integrin Activation
AbstractIntegrin αIIbβ3 is a predominant type of integrin abundantly expressed on the surface of platelets and its activation regulates the process of thrombosis. Talin and kindlin...
Abstract 397: The Interaction of Integrin beta1 to Galpha13 Mediates RhoA Inhibition and Cell Migration
Abstract 397: The Interaction of Integrin beta1 to Galpha13 Mediates RhoA Inhibition and Cell Migration
Background: Integrin-dependent cell migration is critically important in many physiological and pathological processes such as angiogenesis, inflammation, wound healing...
Data from Proapoptotic Function of Integrin β<sub>3</sub> in Human Hepatocellular Carcinoma Cells
Data from Proapoptotic Function of Integrin β<sub>3</sub> in Human Hepatocellular Carcinoma Cells
<div>Abstract<p><b>Purpose:</b> This study evaluates the proapoptotic function of integrin β<sub>3</sub> in human hepatocellular carcinoma (HCC)...
Proapoptotic Function of Integrin β3 in Human Hepatocellular Carcinoma Cells
Proapoptotic Function of Integrin β3 in Human Hepatocellular Carcinoma Cells
Abstract Purpose: This study evaluates the proapoptotic function of integrin β3 in human hepatocellular carcinoma (HCC). Experimental Design: Th...
Data from Proapoptotic Function of Integrin β<sub>3</sub> in Human Hepatocellular Carcinoma Cells
Data from Proapoptotic Function of Integrin β<sub>3</sub> in Human Hepatocellular Carcinoma Cells
<div>Abstract<p><b>Purpose:</b> This study evaluates the proapoptotic function of integrin β<sub>3</sub> in human hepatocellular carcinoma (HCC)...

Back to Top