Circulating adiponectin responses to acute and chronic exercise in obese women

Purpose: The purpose of the present study was to compare the acute effects of moderate and high intensity exercise on adiponectin and also to characterize the chronic effects of exercise on adiponectin in obese and diabetic obese women. Methods: 10 obese women completed a single bout running exercise session at two different exercise intensities (60% vs. 80% V̇O 2 max). 44 obese women with (n=25) and without (n=19) type 2 diabetes were randomly divided into exercise training group (Ex) and control group (Con). Ex group participated in a supervised training program for 12 weeks (4 days a week) consisting of aerobic (60% V̇O 2 R, 30minutes a day) and resistance exercise (10~15RM, 3sets, 30minutes a day). Results: Adiponectin levels were not altered significantly at immediate postexercise, and also there was no significant difference between adiponectin responses to acute moderate and high intensity exercise. Following exercise training, neither obese nor diabetic obese women exhibited changes in TNF‐α and adiponectin levels, but leptin levels were significantly decreased in all exercise groups (p<.01). Conclusion: These results indicate that circulating adiponectin levels do not change with acute exercise and exercise training, regardless of the exercise intensity and type 2 diabetes, respectively. Therefore, we conclude that there are no meaningful acute or chronic effects of exercise on adiponentin levels.