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Semaphorins
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Abstract
The semaphorins are a family of intercellular signalling proteins known to deliver guidance cues to growing axons and migrating cells during development. Semaphorins bind with high affinity to several distinct receptor families, including the neuropilins and plexins.
Title: Semaphorins
Description:
Abstract
The semaphorins are a family of intercellular signalling proteins known to deliver guidance cues to growing axons and migrating cells during development.
Semaphorins bind with high affinity to several distinct receptor families, including the neuropilins and plexins.
Related Results
Semaphorins
Semaphorins
Abstract
The semaphorins are an evolutionary conserved family of intercellular signalling proteins known to deliver guidance cues to growing axo...
Origin and evolution of plexins, semaphorins, and Met receptor tyrosine kinases
Origin and evolution of plexins, semaphorins, and Met receptor tyrosine kinases
AbstractThe transition from unicellular to multicellular organisms poses the question as to when genes that regulate cell-cell interactions emerged during evolution. The receptor a...
Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis
Diverse gene expression and function of semaphorins in developing lung: positive and negative regulatory roles of semaphorins in lung branching morphogenesis
Background Previously, we reported that Sema3A, one of the secreted repulsive axon guidance molecules, CRMP (collapsin response mediator protein)‐2, a putative intracellular signal...
Semaphorins and Plexins in Kidney Disease
Semaphorins and Plexins in Kidney Disease
Semaphorins are soluble or membrane-bound cues, which control multiple aspects of cell-cell communication, differentiation, morphology and function. Most of their effects are media...
Molecular mechanisms of proteoglycan-mediated semaphorin signaling in axon guidance
Molecular mechanisms of proteoglycan-mediated semaphorin signaling in axon guidance
The precise assembly of a functional nervous system relies on axon guidance cues. Beyond engaging their cognate receptors and initiating signaling cascades that modulate cytoskelet...
Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning
Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning
Abstract
Semaphorin ligands and their plexin receptors are one of the major cell guidance factors that trigger localised changes in the cytos...
The Plexin PLX-2 and the Ephrin EFN-4 Have Distinct Roles in MAB-20/Semaphorin 2A Signaling in Caenorhabditis elegans Morphogenesis
The Plexin PLX-2 and the Ephrin EFN-4 Have Distinct Roles in MAB-20/Semaphorin 2A Signaling in Caenorhabditis elegans Morphogenesis
Abstract
Semaphorins are extracellular proteins that regulate axon guidance and morphogenesis by interacting with a variety of cell surface receptors. Most semaphori...
Semaphorins
Semaphorins
Abstract
The semaphorins are a family of intercellular signalling proteins known to deliver guidance cues to growing axons during development. Semaphorins bind with high ...