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Clinical and morphological features of desmoid-type fibromatosis
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In order to study the clinical and morphological features of fibromatosis of the desmoid type, a literature review was conducted. It was found that fibromatosis of the desmoid type is a locally ag-gressive myofibroblastic tumor that occurs in muscular-aponeurotic structures. The clinical picture is affected by the localization of the tumor and its invasive growth into the surrounding tissues.
The complexity of diagnosis is due to the rarity and morphological similarity to soft tissue sarcomas. Immunohistochemical research is used to exclude malignancy. It was found that the features of fibromatosis of the desmoid type are characterized by pronounced diffuse nuclear expression of beta-catenin, reactions to DOG1, CD117, S-100 and SMA are negative.
Yakutsk Scientific Center for Complex Medical Problems
Title: Clinical and morphological features of desmoid-type fibromatosis
Description:
In order to study the clinical and morphological features of fibromatosis of the desmoid type, a literature review was conducted.
It was found that fibromatosis of the desmoid type is a locally ag-gressive myofibroblastic tumor that occurs in muscular-aponeurotic structures.
The clinical picture is affected by the localization of the tumor and its invasive growth into the surrounding tissues.
The complexity of diagnosis is due to the rarity and morphological similarity to soft tissue sarcomas.
Immunohistochemical research is used to exclude malignancy.
It was found that the features of fibromatosis of the desmoid type are characterized by pronounced diffuse nuclear expression of beta-catenin, reactions to DOG1, CD117, S-100 and SMA are negative.
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