ROLE OF ASPIRIN AS PROPHYLAXIS AGAINST COLORECTAL CANCER

Introduction: Colorectal cancer (Bowel Cancer) is cancer of colon and rectum that are the parts of large intestine. [1] Symptoms are pain on defecation, blood and mucus in feces.[2] Risk factors of colon cancer are certain diet that is red meat, alcohol, and meat that is processed, obesity, smoking, and lack of physical activity.[3, 4]. Others factors are old age, type three personalities and usage of spicy foods. People with inflammatory bowel disease (ulcerative colitis and Crohn's disease), familial adenomatous polyposis are at high threat of cancer of colon and rectum. This can be prevented by using aspirin usage in long term.[5,6,7]. In high danger families, cancer of colon can be prevented by using aspirin and colonoscopies are recommended in these families.[8,9] Colorectal cancer can be diagnosed by sigmoidoscopy or colonoscopy.[10,11,12] .Most of people (50 %) do not report any signs and symptoms of colon cancer.[13,14]. Streptococcus gallolyticus is associated with colorectal cancer.[15, 16] Objective: To find out the role of aspirin as prophylaxis against colorectal cancer. Methodology: This descriptive retrospective study was conducted in the Ibnae –Sienna Hospital Multan from January 2016 to August 2017. 100 patients of each group between 50-65 years of age were included in the study; all were male whose were taken aspirin for pain killer and for fever as routine since long term and 100 male patients of same age not used aspirin. Date analysis was carried out using SPSS version 19 Software. Results: All were male patients 100 (100 %) 50-65 years of age. Most of the patients (98) 98 % who used aspirin in the past have no colorectal cancer as compared to patients (18) 18 % who not taken aspirin in the past have colorectal cancer. Conclusion: Patients used aspirin since long have very least possibilities of colorectal cancer