Effect of Dietary Sumac (Rhus coriaria L.) Supplementation on Non-Specific Immune Response and Hematology of Rainbow Trout (Oncorhynchus mykiss), Resistance Against Vibrio anguillarum

This study aimed to investigate the effects of sumac (Rhus coriaria L.) fruit powder in different concentrations as feed additives on non-specific immune response, hematology, and the disease resistance in rainbow trout (Oncorhynchus mykiss). Fish (35.67±0.88 g) were fed with experimental diets (1.0, 3.0, 5.0 and 10.0 g kg-1) at four different concentration. There were no significant differences between groups fed with sumac fruit powder and control group by the mean of red blood cell count (RBC), white blood cell count (WBC), differential leukocytes count (monocyte, lymphocyte, and neutrophile), hematocrit (Hct), hemoglobin (Hb), cell hemoglobin (MCH pg), cell hemoglobin concentration (MCHC %), cell hemoglobin volume (MCV µm3) and plasma lysozyme, Immunoglobulin M (IgM), total protein level on the 8 weeks. After 8 weeks of feeding, fish were challenged with Vibrio anguillarum and cumulative mortality was recorded over 21 days. Dietary administration of 1.0, 3.0, and 5.0 g kg−1 sumac fruit powder significantly increased fish survival rate (p<0.05). The 10.0 g kg−1 diet received fish showed no mortality post challenged with V. anguillarum. These results showed that the sumac fruit powder improved disease resistance when added to the rainbow trout diet