Characteristics and risk factors for deep vein thrombosis in patients with lower limb motor impairment after ischemic stroke: A retrospective study

Abstract Objective To analyze the characteristics and risk factors of deep vein thrombosis (DVT) in the lower extremities of patients with lower limb motor disorders after ischemic stroke within one year after discharge. Methods A total of 159 patients with lower limb motor disorders after ischemic stroke who were treated in the rehabilitation department of Nanjing Drum Tower Hospital from October 2023 to October 2025 were collected. The occurrence of lower extremity DVT within one year of follow-up was statistically analyzed. Patients were divided into the DVT group (n = 57) and the control group (n = 102) based on whether they developed lower extremity DVT within one year after discharge. The clinical characteristics of the two groups were compared to analyze the characteristics and risk factors of DVT in patients with lower limb motor disorders after ischemic stroke. Results Among the 159 patients with ischemic stroke and hemiplegia, 4 cases (2.51%), 13 cases (8.17%), 28 cases (17.61%), 42 cases (26.42%), and 57 cases (35.84%) developed lower extremity DVT during hospitalization for stroke, within one month after discharge, within three months after discharge, within six months after discharge, and within one year after discharge, respectively. Multivariate analysis showed that age, hypertension, hyperlipidemia, type 2 diabetes, and D-dimer were independent risk factors for the occurrence of lower extremity DVT within one year in patients with ischemic stroke and lower limb motor disorders (P < 0.05). Conclusion The incidence of lower extremity DVT in patients with acute ischemic stroke and hemiplegia shows a significant increasing trend over time. Age, hypertension, hyperlipidemia, type 2 diabetes, and D-dimer increase the risk of lower extremity DVT within one year in patients with ischemic stroke and lower limb motor disorders.