Seroprevalence of parvovirus infections from vaccinated and unvaccinated dogs of Andhra Pradesh

The present study aimed to assess the presence of Canine parvovirus 2 (CPV-2) antibodies in both vaccinated and unvaccinated dogs. The canine parvovirus disease in dogs was monitored by the use of live attenuated and killed vaccines besides new generation vaccines were also being developed for the control strategy. A total of 542 serum samples from different regions of Andhra Pradesh were used for the study. The age, sex, breed, and vaccination status were noted. The seroprevalence of canine parvovirus infection was studied by employing the methods of indirect ELISA and haemagglutination inhibition (HI) assay. The CPV infection rate was recorded as 94.65% in vaccinated and 72.50% in unvaccinated by indirect ELISA. Haemagglutination inhibition assay could detect 56.10% in vaccinated and 16.42% in unvaccinated ones. The titres ranged from 419 to 2337. Vaccinated dogs had more antibodies than the unvaccinated ones thus indicating the presence of antibodies in all the dogs suggesting that CPV infection is ubiquitous and natural infection of CPV aids in boosting immunity.