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Nucleotide sequence of a cDNA clone (SUBT1) partly homologous to a human subtelomeric repeat sequence
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AbstractTelomeres contains short tandem repeats (TTAGGG)n that are usually several kilobases in size. DNA sequences located next to the repeats are called telomere‐associated or subtelomeric sequences. In this report we describe isolation and characterization of a new cDNA sequence isolated with a telomere specific, chromosome 17 genomic clone. No open reading frame of notable length could be detected. However comparison with sequences in the EMBL/Genbank revealed a 897 bp of close to perfect match, in the 3′ end with the centromeric end of a genomic clone containing subtelomeric repeat sequences. The potential function of the SUBT1 transcript remains to be elucidated.
Title: Nucleotide sequence of a cDNA clone (SUBT1) partly homologous to a human subtelomeric repeat sequence
Description:
AbstractTelomeres contains short tandem repeats (TTAGGG)n that are usually several kilobases in size.
DNA sequences located next to the repeats are called telomere‐associated or subtelomeric sequences.
In this report we describe isolation and characterization of a new cDNA sequence isolated with a telomere specific, chromosome 17 genomic clone.
No open reading frame of notable length could be detected.
However comparison with sequences in the EMBL/Genbank revealed a 897 bp of close to perfect match, in the 3′ end with the centromeric end of a genomic clone containing subtelomeric repeat sequences.
The potential function of the SUBT1 transcript remains to be elucidated.
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