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ANALYSIS OF TIME TO FAILURE AFTER RETINAL DETACHMENT SURGERY
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Purpose:
To present the distribution of time to retinal redetachment in eyes undergoing retinal detachment surgery, using a method for adjusting time to outcome in eyes with silicone oil or heavy liquid tamponade (“oil-filled eyes”).
Methods:
Data from two Australian centers were used. Adjusted time to outcome was measured from the date of tamponade removal in oil-filled eyes, unless failure was diagnosed with tamponade in situ.
Results:
188/1257 failures were identified (15.0%). Using unadjusted time to outcome, failures in oil-filled eyes occurred later than non–oil-filled eyes (median time to failure 57 vs. 28 days, P < 0.001). After adjustment, the distribution of time to failure was similar for oil-filled and non–oil-filled eyes (median 25 vs. 28 days, P = 0.68). Larger detachments, eyes with ≥Grade B proliferative vitreoretinopathy and eyes receiving surgery for recurrent detachments were more likely to fail, but the time to failure was similar regardless of risk.
Conclusion:
Adjustment of time to outcome resulted in a similar distribution of time to failure in oil-filled and non–oil filled eyes and was similar in low- and high-risk eyes. The use of adjusted time to outcome will support consistent collection and interpretation of outcomes across different jurisdictions where time to oil removal may vary.
Ovid Technologies (Wolters Kluwer Health)
Title: ANALYSIS OF TIME TO FAILURE AFTER RETINAL DETACHMENT SURGERY
Description:
Purpose:
To present the distribution of time to retinal redetachment in eyes undergoing retinal detachment surgery, using a method for adjusting time to outcome in eyes with silicone oil or heavy liquid tamponade (“oil-filled eyes”).
Methods:
Data from two Australian centers were used.
Adjusted time to outcome was measured from the date of tamponade removal in oil-filled eyes, unless failure was diagnosed with tamponade in situ.
Results:
188/1257 failures were identified (15.
0%).
Using unadjusted time to outcome, failures in oil-filled eyes occurred later than non–oil-filled eyes (median time to failure 57 vs.
28 days, P < 0.
001).
After adjustment, the distribution of time to failure was similar for oil-filled and non–oil-filled eyes (median 25 vs.
28 days, P = 0.
68).
Larger detachments, eyes with ≥Grade B proliferative vitreoretinopathy and eyes receiving surgery for recurrent detachments were more likely to fail, but the time to failure was similar regardless of risk.
Conclusion:
Adjustment of time to outcome resulted in a similar distribution of time to failure in oil-filled and non–oil filled eyes and was similar in low- and high-risk eyes.
The use of adjusted time to outcome will support consistent collection and interpretation of outcomes across different jurisdictions where time to oil removal may vary.
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