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Etiologies of Hemodynamically Significant Aortic Regurgitation and Coronary Cusp Bending: Evaluation by Transesophageal Echocardiography

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Background: While the number of patients with aortic regurgitation (AR) has been increasing in the aging society, its etiologies remain to be fully elucidated. Methods: We studied consecutive 126 patients with chronic moderate or severe AR who underwent TEE. After the study subjects were divided into 2 groups by the age of 65 years, AR etiology was examined in each group. Results: In the older group (n = 85), cusp bending was the most frequent cause of AR (48.2%), and right coronary cusp (RCC) was the most common (90.2%). In the younger group (n=41), bicuspid valve was the most frequent cause (36.5%), and cusp bending was less frequent (16.5%). Multivariate analysis revealed that age was the only factor associated with cusp bending. Conclusion: Cusp bending of RCC was the most frequent etiology of AR in the elderly. Because AR caused by cusp bending has a possibility to be mended by aortic plasty, it is important to detect it by TEE especially in the older patients.
Title: Etiologies of Hemodynamically Significant Aortic Regurgitation and Coronary Cusp Bending: Evaluation by Transesophageal Echocardiography
Description:
Background: While the number of patients with aortic regurgitation (AR) has been increasing in the aging society, its etiologies remain to be fully elucidated.
Methods: We studied consecutive 126 patients with chronic moderate or severe AR who underwent TEE.
After the study subjects were divided into 2 groups by the age of 65 years, AR etiology was examined in each group.
Results: In the older group (n = 85), cusp bending was the most frequent cause of AR (48.
2%), and right coronary cusp (RCC) was the most common (90.
2%).
In the younger group (n=41), bicuspid valve was the most frequent cause (36.
5%), and cusp bending was less frequent (16.
5%).
Multivariate analysis revealed that age was the only factor associated with cusp bending.
Conclusion: Cusp bending of RCC was the most frequent etiology of AR in the elderly.
Because AR caused by cusp bending has a possibility to be mended by aortic plasty, it is important to detect it by TEE especially in the older patients.

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