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Metode Deteksi Carbapenem Resistant Enterobacteriaceae
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Carbapenem Resistant Enterobacteriaceae (CRE) merupakan kelompok bakteri Enterobacteriaceae yang resisten terhadap antibiotik golongan Carbapenem (Imipenem, Ertapenem, Meropenem, Doripenem). Salah satu spesies Enterobacteriaceae yang sering menunjukkan sifat resisten terhadap Carbapenem adalah Klebsiella pneumoniae. Untuk mendeteksi keberadaan CRE perlu dilakukan deteksi dini menggunakan uji fenotip dan genotip. Uji fenotip yang dapat dilakukan adalah Modified Hodge Test (MHT), Carba Nordmann-Poirel (Carba NP), dan Modified Carbapenem Inactivation Method (MCIM). Untuk mengetahui keberadaan gen penyandi enzim carbapememase, metoda yang dapat dipakai dalam uji genotip adalah metoda Polymerase Chain Reaction (PCR)
Kata kunci : Carbapenem Resistant Enterobacteriaceae (CRE), Fenotip, Genotip, Modified Carbapenem Inactivation Method (MCIM), Modified Hodge Test (MHT), Carba NP, Polymerase Chain Reaction (PCR).
Title: Metode Deteksi Carbapenem Resistant Enterobacteriaceae
Description:
Carbapenem Resistant Enterobacteriaceae (CRE) merupakan kelompok bakteri Enterobacteriaceae yang resisten terhadap antibiotik golongan Carbapenem (Imipenem, Ertapenem, Meropenem, Doripenem).
Salah satu spesies Enterobacteriaceae yang sering menunjukkan sifat resisten terhadap Carbapenem adalah Klebsiella pneumoniae.
Untuk mendeteksi keberadaan CRE perlu dilakukan deteksi dini menggunakan uji fenotip dan genotip.
Uji fenotip yang dapat dilakukan adalah Modified Hodge Test (MHT), Carba Nordmann-Poirel (Carba NP), dan Modified Carbapenem Inactivation Method (MCIM).
Untuk mengetahui keberadaan gen penyandi enzim carbapememase, metoda yang dapat dipakai dalam uji genotip adalah metoda Polymerase Chain Reaction (PCR)
Kata kunci : Carbapenem Resistant Enterobacteriaceae (CRE), Fenotip, Genotip, Modified Carbapenem Inactivation Method (MCIM), Modified Hodge Test (MHT), Carba NP, Polymerase Chain Reaction (PCR).
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