Sustainable Drug Delivery Systems with Biodegradable Innovations for Targeted and Efficient Therapy

Development of drug delivery systems has introduced environmentally friendly and degradable technology due to the advent of targeted, effective, and sustainable therapies. Recent advances on biodegradable polymers, nanotechnology-based smart carriers, and AI-based personalized medicine are being presented here and are all setting the platform for the next-generation drug delivery system. Use of biodegradable material reduces environmental burden but increases drug stability, bioavailability, and controlled release. Nanotechnology has revolutionized site-specific drug delivery with responsive drug delivery systems delivering drugs at desired locations, reducing toxicity and maximizing therapeutic efficacy. Natural and plant molecules are becoming more commonly used as green drug excipients and also improving biocompatibility and less synthetic waste. In addition, advances in AI-based drug design and precision medicine are allowing therapy to be personalized to the patient, improving treatment efficacy with reduced side effects. In antibiotic resistance management, novel nanotechnology-based drugs and drug delivery systems offer enhanced bacterial targeting and enhanced drug retention to overcome the top clinical challenges. Green and biodegradable drug delivery will be at the forefront of future pharmaceutical science with AI, nanotechnology, and green excipients being the pioneers. In this review, emphasis is placed on the future of such novel technologies to re-define drug delivery with patient safety and environmental sustainability at its core.