Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Aldose Reductase Inhibitory Activity Studies of Substituted 3-Sulfenylindoles
View through CrossRef
Sulfenylindoles obtained by direct sulfenylation of indoles using diphenyl disulphide in the presence of catalytic amount of iodine in DMSO have been studied for aldose reductase inhibitory activity. As expected, different 3-sulfenylindoles derivatives that are synthesized exhibit good-to-excellent aldose reductase inhibitory activity.
Asian Journal of Chemistry
Title: Aldose Reductase Inhibitory Activity Studies of Substituted 3-Sulfenylindoles
Description:
Sulfenylindoles obtained by direct sulfenylation of indoles using diphenyl disulphide in the presence of catalytic amount of iodine in DMSO have been studied for aldose reductase inhibitory activity.
As expected, different 3-sulfenylindoles derivatives that are synthesized exhibit good-to-excellent aldose reductase inhibitory activity.
Related Results
Identificação de potenciais candidatos a fármacos com afinidade frente a Aldose Redutase humana
Identificação de potenciais candidatos a fármacos com afinidade frente a Aldose Redutase humana
Introdução: A diabetes mellitus (DM) é uma doença crônica que se manifesta a partir da inatividade ou redução dos níveis de insulina no organismo, com consequente elevação da glice...
Human aldose reductase unfolds through an intermediate.
Human aldose reductase unfolds through an intermediate.
Background:
Human aldose reductase (hAR) converts glucose to sorbitol under hyperglycemic conditions. Aldose reductase is first and rate limiting enzyme of poly...
Genetic restoration of aldose reductase to the collecting tubules restores maturation of the urine concentrating mechanism
Genetic restoration of aldose reductase to the collecting tubules restores maturation of the urine concentrating mechanism
To investigate the underlying causes for aldose reductase deficiency-induced diabetes insipidus, we carried out studies with three genotypic groups of mice. These included wild-typ...
Evaluating the Science to Inform the Physical Activity Guidelines for Americans Midcourse Report
Evaluating the Science to Inform the Physical Activity Guidelines for Americans Midcourse Report
Abstract
The Physical Activity Guidelines for Americans (Guidelines) advises older adults to be as active as possible. Yet, despite the well documented benefits of physical a...
DIFFERENT ASPECTS OF 5α‐REDUCTASE DEFICIENCY IN MALE PSEUDOHERMAPHRODITISM AND HYPOTHYROIDISM
DIFFERENT ASPECTS OF 5α‐REDUCTASE DEFICIENCY IN MALE PSEUDOHERMAPHRODITISM AND HYPOTHYROIDISM
SUMMARYThe 5α‐reductase activity that mediates the transformation of testosterone to dihydrotestosterone in various anatomical sites of human beings, has been studied in different ...
Development and Exploration of Organic Compounds as Aldose Reductase Inhibitors: An Overview
Development and Exploration of Organic Compounds as Aldose Reductase Inhibitors: An Overview
Abstract:
Changes in the body's natural glucose levels have been associated with the onset of diabetes
mellitus. It is frequently accompanied by a number of long-term consequences,...
Aldose reductase gene polymorphism rs752010122 and retinopathy in type 2 diabetics
Aldose reductase gene polymorphism rs752010122 and retinopathy in type 2 diabetics
Objective: To investigate the association of polymorphism in rs752010122 in aldose reductase gene with the pathogenesis of diabetic retinopathy, and to determine the association an...
Synthesis and Aldose Reductase Inhibitory Activities of Novel O‐Substituted Hydroxyphenylacetic Acid Derivatives
Synthesis and Aldose Reductase Inhibitory Activities of Novel O‐Substituted Hydroxyphenylacetic Acid Derivatives
AbstractIn continuation of our work aimed towards the preparation of novel aldose reductase inhibitors, several O‐substituted hydroxyphenylacetic acid derivatives were investigated...