Clinicopathological features and surgical treatment of thyroid papillary carcinoma in Hashimoto thyroiditis

Background and Aim: Papillary thyroid carcinoma (PTC) is the most prevalent types of thyroid cancer. The present study aimed to investigate the clinicopathological features and surgical treatment of thyroid papillary carcinoma in Hashimoto thyroiditis. Patients and Methods: A cross-sectional study was carried out on 486 papillary thyroid carcinoma patients in the surgical department of Mardan Medical Complex, Mardan Pakistan from March 2020 to March 2023. All the patients were categorized into two groups: Group-I (papillary thyroid carcinoma with Hashimoto thyroiditis) and Group-II (papillary thyroid carcinoma without Hashimoto thyroiditis). Serum thyroid-stimulating hormone (TSH), age, central compartment lymph node metastasis (CLNM), gender, nodular size, and invasive status were different clinicopathological factors recorded. SPSS version 27 was used for data analysis. Results: The overall mean age was 42.84±10.8 years. Out of 486 patients, Group-I had 76 (15.6%) patients whereas Group-II had 410 (84.4%) patients. There were 52 (10.7%) male and 434 (89.3%) females. The incidence of final diagnosis of benign thyroid nodule and PTC was 53.9% (n=262) and 46.1% (n=224) respectively. The prevalence of PT in Group-I was significantly higher 56.8% 57.9% (n=44) than in Group-II 43.4% (n=178).