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Corey‐Fuchs Reaction
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Abstract
This reaction is a two‐step process to prepare a terminal alkyne with one‐carbon homologation of an aldehyde or to prepare an alkyne derivative by the treatment of the alkynide intermediate with an electrophile before an aqueous workup and is generally known as the Corey–Fuchs reaction.Because dihaloalkene is formed as a reaction intermediate that can be obtained before the treatment with a strong base, this reaction is also referred to as the Corey‐Fuchs olefination. The zinc dust has also been added in this reaction to prepare dibromoalkene with an improved yield.
Title: Corey‐Fuchs Reaction
Description:
Abstract
This reaction is a two‐step process to prepare a terminal alkyne with one‐carbon homologation of an aldehyde or to prepare an alkyne derivative by the treatment of the alkynide intermediate with an electrophile before an aqueous workup and is generally known as the Corey–Fuchs reaction.
Because dihaloalkene is formed as a reaction intermediate that can be obtained before the treatment with a strong base, this reaction is also referred to as the Corey‐Fuchs olefination.
The zinc dust has also been added in this reaction to prepare dibromoalkene with an improved yield.
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