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Legionnaires' Disease with Facial Nerve Palsy
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Legionnaires' disease is primarily a pneumonic process caused byLegionella pneumophilia, a gram-negative aerobic bacillus but also has multiple system involvement. The most common manifestation is encephalopathy suggesting a generalized brain dysfunction but focal neurological manifestations have been reported. We report a patient with Legionella pneumonia associated with cerebellar dysfunction and unilateral facial nerve weakness. 51-year-old previously healthy male presented with shortness of breath, cough, slurred speech, and unsteadiness on feet associated with malaise, fevers and myalgias. Patient's family reported facial asymmetry for 2 days. Patient had no significant medical history and was not on any medication. He denied smoking, alcohol or illicit drug use. Chest X-ray showed bilateral lower lobe infiltrates. Urinary antigen assay forLegionella pneumophiliaserogroup 1 was positive. Patient was started on intravenous moxifloxacin. On day 5 the patient was discharged home and continued oral moxifloxacin for two weeks. After the two weeks, his respiratory symptoms, gait ataxia and dysarthria resolved. We report the first case of Legionnaires' disease with cerebellar dysfunction and seventh nerve palsy. Legionnaires' disease should be considered in patients with any neurological symptoms in the setting of pneumonia. Failure to recognize and treat the infection may lead to poor outcomes.
Title: Legionnaires' Disease with Facial Nerve Palsy
Description:
Legionnaires' disease is primarily a pneumonic process caused byLegionella pneumophilia, a gram-negative aerobic bacillus but also has multiple system involvement.
The most common manifestation is encephalopathy suggesting a generalized brain dysfunction but focal neurological manifestations have been reported.
We report a patient with Legionella pneumonia associated with cerebellar dysfunction and unilateral facial nerve weakness.
51-year-old previously healthy male presented with shortness of breath, cough, slurred speech, and unsteadiness on feet associated with malaise, fevers and myalgias.
Patient's family reported facial asymmetry for 2 days.
Patient had no significant medical history and was not on any medication.
He denied smoking, alcohol or illicit drug use.
Chest X-ray showed bilateral lower lobe infiltrates.
Urinary antigen assay forLegionella pneumophiliaserogroup 1 was positive.
Patient was started on intravenous moxifloxacin.
On day 5 the patient was discharged home and continued oral moxifloxacin for two weeks.
After the two weeks, his respiratory symptoms, gait ataxia and dysarthria resolved.
We report the first case of Legionnaires' disease with cerebellar dysfunction and seventh nerve palsy.
Legionnaires' disease should be considered in patients with any neurological symptoms in the setting of pneumonia.
Failure to recognize and treat the infection may lead to poor outcomes.
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