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Immunohistochemical expression of IL‐10 in mycosis fungoides
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Abstract Immunoreactivity of the cytokine IL‐10 has been investigated in situ in mycosis fungoides (MF). Expression of IL‐10 was detected using immunohistochemistry in skin biopsies (n=8) and T‐cell lines (n= 2) from mycosis fungoides patients. IL‐10 positivily was seen in the dermal cell infiltrates and in T‐cell lines in mycosis fungoides. The dermal IL‐10 reaction in a skin biopsy from an active lesion in MF indicates the possibility for disease progression.
Title: Immunohistochemical expression of IL‐10 in mycosis fungoides
Description:
Abstract Immunoreactivity of the cytokine IL‐10 has been investigated in situ in mycosis fungoides (MF).
Expression of IL‐10 was detected using immunohistochemistry in skin biopsies (n=8) and T‐cell lines (n= 2) from mycosis fungoides patients.
IL‐10 positivily was seen in the dermal cell infiltrates and in T‐cell lines in mycosis fungoides.
The dermal IL‐10 reaction in a skin biopsy from an active lesion in MF indicates the possibility for disease progression.
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