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A COMPARISON OF NEBULIZED AND INTRAVENOUS LIDOCAINE FOR REDUCING BLOOD PRESSURE CHANGES DURING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION.
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Background: Laryngoscopy and endotracheal intubation often lead to temporary increases in blood pressure and heart rate due to the activation of
the sympatho-adrenal system. Patients with cardiovascular and cerebrovascular illnesses may have a sudden hemodynamic reaction, which may
have harmful consequences such as myocardial ischemia or infarction, arrhythmias, cardiac failure, increased intracranial pressure, and cerebral
hemorrhage. Aim: A comparison of nebulized and intravenous lidocaine for reducing blood pressure changes during laryngoscopy and
endotracheal intubation Materials and method: Aprospective randomized study was done in the Department of Anaesthesia and Critical Care at
K. D. Medical College Hospital and Research Center, Mathura, from June 2023 to Jan 2024. Ninety patients undergoing surgeries under general
anesthesia were divided into two groups. Patients of group IVL (n=45) received 2% Lignocaine 1.5mg/kg diluted in 10ml Normal saline by slow
intravenous route 90 seconds before induction, and patients of group NL (n=45) received 4ml, 4% lignocaine as nebulization 10min before
induction.Results: In Group NL, the baseline heart rate (HR) was 87.04 bpm, increasing to 112.47 bpm two minutes post-intubation, indicating a
rise of 25.43 bpm. In the IVL group, the baseline HR for this group was 87.63 bpm, with a subsequent increase to 100.02 bpm two minutes postintubation, reecting a rise of 12.39 bpm.In the NL group, nebulized lignocaine signicantly increased systolic (SBP), diastolic (DBP), and mean
arterial pressure (MAP) by notable values as compared with the IVL group. Conclusion: Our conclusion is that the administration of lignocaine
effectively mitigates the uctuations in heart rate and blood pressure induced by laryngoscopy and endotracheal intubation. Notably, the
intravenous delivery of lignocaine demonstrates superior suppressive properties when compared to lignocaine nebulization.
Title: A COMPARISON OF NEBULIZED AND INTRAVENOUS LIDOCAINE FOR REDUCING BLOOD PRESSURE CHANGES DURING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION.
Description:
Background: Laryngoscopy and endotracheal intubation often lead to temporary increases in blood pressure and heart rate due to the activation of
the sympatho-adrenal system.
Patients with cardiovascular and cerebrovascular illnesses may have a sudden hemodynamic reaction, which may
have harmful consequences such as myocardial ischemia or infarction, arrhythmias, cardiac failure, increased intracranial pressure, and cerebral
hemorrhage.
Aim: A comparison of nebulized and intravenous lidocaine for reducing blood pressure changes during laryngoscopy and
endotracheal intubation Materials and method: Aprospective randomized study was done in the Department of Anaesthesia and Critical Care at
K.
D.
Medical College Hospital and Research Center, Mathura, from June 2023 to Jan 2024.
Ninety patients undergoing surgeries under general
anesthesia were divided into two groups.
Patients of group IVL (n=45) received 2% Lignocaine 1.
5mg/kg diluted in 10ml Normal saline by slow
intravenous route 90 seconds before induction, and patients of group NL (n=45) received 4ml, 4% lignocaine as nebulization 10min before
induction.
Results: In Group NL, the baseline heart rate (HR) was 87.
04 bpm, increasing to 112.
47 bpm two minutes post-intubation, indicating a
rise of 25.
43 bpm.
In the IVL group, the baseline HR for this group was 87.
63 bpm, with a subsequent increase to 100.
02 bpm two minutes postintubation, reecting a rise of 12.
39 bpm.
In the NL group, nebulized lignocaine signicantly increased systolic (SBP), diastolic (DBP), and mean
arterial pressure (MAP) by notable values as compared with the IVL group.
Conclusion: Our conclusion is that the administration of lignocaine
effectively mitigates the uctuations in heart rate and blood pressure induced by laryngoscopy and endotracheal intubation.
Notably, the
intravenous delivery of lignocaine demonstrates superior suppressive properties when compared to lignocaine nebulization.
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