ASSESSMENT OF PSYCHO-EMOTIONAL DISORDERS AND QUALITY OF LIFE IN PATIENTS WITH CHRONIC PROSTATITIS / CHRONIC PELVIC PAIN SYNDROME

Chronic prostatitis / chronic pelvic pain syndrome remains one of the most prevalent urological disorders in men of reproductive age and is frequently accompanied by psychoemotional disturbances and a significant decline in quality of life. Despite extensive investigation, the role of affective and neuropathic mechanisms in the development and maintenance of pain in сhronic prostatitis / chronic pelvic pain syndrome has not been sufficiently elucidated.Objective: To assess the prevalence and intensity of psychoemotional disorders and to determine the relationship between depressive symptoms and the neuropathic component of pain in patients with сhronic prostatitis / chronic pelvic pain syndrome. Material and methods. A total of 128 men aged 22–40 years diagnosed with сhronic prostatitis / chronic pelvic pain syndrome were examined. Psychoemotional status was assessed using the PHQ-9 and GAD-7 questionnaires; the neuropathic component of pain was evaluated using the DN4 scale, and quality of life was measured with the EQ-5D questionnaire. Statistical analysis was performed using the Kruskal–Wallis test, Dunn’s post hoc test, and correlation analysis.Result: Clinically significant depressive symptoms were detected in 68% of patients, while 61% demonstrated elevated anxiety levels. The mean PHQ-9 and GAD-7 scores were 11.2±4.5 and 9.8±3.7, respectively, indicating a moderate degree of affective disturbance. Depression severity increased proportionally with higher NIH-CPSI scores (p<0.001) and was associated with reduced EQ-5D quality-of-life indices (p<0.01). A strong positive correlation was found between depressive symptoms (PHQ-9) and the neuropathic pain score (DN4) (r=0.87; p<0.001), highlighting the close interaction between affective dysregulation and sensory mechanisms in the pathophysiology of chronic pelvic pain.Conclusions. Psychoemotional disorders represent a common and clinically significant component of сhronic prostatitis / chronic pelvic pain syndrome. Their severity is closely related to the intensity of pain and the presence of neuropathic mechanisms, underscoring the need for a multidisciplinary management approach that integrates psychoemotional screening and targeted correction of affective disturbances.