Search engine for discovering works of Art, research articles, and books related to Art and Culture
Javascript must be enabled to continue!
Influence of yeast mannan on release of myeloperoxidase by human neutrophils: determination of structural features of mannan required for formation of myeloperoxidase-mannan-neutrophil complexes
View through CrossRef
Structural features of mannan which participate in the formation of myeloperoxidase-mannan-neutrophil complexes have been studied by using a battery of structurally modified mannans. Mannan was isolated from Saccharomyces cerevisiae X2180 wild type and modified by strong alkaline degradation, selective (mild) alkaline degradation, and selective acetolysis. Mannose oligosaccharides bound to the peptide portion of mannan appeared to be required for binding of mannan to the neutrophil. The interaction of mannan with myeloperoxidase appeared to occur through phosphate groups of the mannan outer chain. The myeloperoxidase-mannan interaction was determined to be ionic in nature. The mannan-neutrophil interaction may involve cell membrane receptors for mannose.
Title: Influence of yeast mannan on release of myeloperoxidase by human neutrophils: determination of structural features of mannan required for formation of myeloperoxidase-mannan-neutrophil complexes
Description:
Structural features of mannan which participate in the formation of myeloperoxidase-mannan-neutrophil complexes have been studied by using a battery of structurally modified mannans.
Mannan was isolated from Saccharomyces cerevisiae X2180 wild type and modified by strong alkaline degradation, selective (mild) alkaline degradation, and selective acetolysis.
Mannose oligosaccharides bound to the peptide portion of mannan appeared to be required for binding of mannan to the neutrophil.
The interaction of mannan with myeloperoxidase appeared to occur through phosphate groups of the mannan outer chain.
The myeloperoxidase-mannan interaction was determined to be ionic in nature.
The mannan-neutrophil interaction may involve cell membrane receptors for mannose.
Related Results
Trans-epithelial migration is essential for neutrophil activation during RSV infection
Trans-epithelial migration is essential for neutrophil activation during RSV infection
Abstract
The recruitment of neutrophils to the infected airway occurs early following respiratory syncytial virus (RSV) infection and high number...
“Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage
“Rogue” [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage
ObjectiveCumulative clinical, cellular, and molecular evidence reinforces the role of neutrophils in secondary brain injury in spontaneous intracerebral hemorrhage (sICH). However,...
High plasma concentration of myeloperoxidase in cirrhosis: A possible marker of hypersplenism
High plasma concentration of myeloperoxidase in cirrhosis: A possible marker of hypersplenism
Plasma myeloperoxidase levels in patients with cirrhosis were compared with those in patients with chronic hepatitis and healthy controls by means of a specific radioimmunoassay fo...
Neutrophil Proteinase (PR3) Regulates Neutrophil Transendothelial Cell Migration.
Neutrophil Proteinase (PR3) Regulates Neutrophil Transendothelial Cell Migration.
Abstract
Abstract 1492
Neutrophil transmigration requires the localization of neutrophils to endothelial cell junctions where receptor-ligand interact...
“Rogue” neutrophil-subset [DEspR+CD11b+/CD66b+] immunotype is an actionable therapeutic target for neutrophilic inflammation-mediated tissue injury – studies in human, macaque and rat LPS-inflammation models
“Rogue” neutrophil-subset [DEspR+CD11b+/CD66b+] immunotype is an actionable therapeutic target for neutrophilic inflammation-mediated tissue injury – studies in human, macaque and rat LPS-inflammation models
Background and objectiveThe correlation (Rs > 0.7) of neutrophils expressing the dual endothelin1/signal peptide receptor (DEspR+CD11b+/CD66b+) with severity of hypoxemia (S...
Heme Induces Significant Neutrophil Adhesion in Vitro Via an Nfκb-Dependent Pathway
Heme Induces Significant Neutrophil Adhesion in Vitro Via an Nfκb-Dependent Pathway
Abstract
Background: Intravascular hemolysis, a major complication of sickle cell anemia and malaria among other diseases, incurs the release of excessive quantities...
Histamine production by human neutrophils
Histamine production by human neutrophils
Histamine is an important mediator in the development of allergic reactions. Only a small subset of human cell types is able to produce histamine. No previous studies have shown th...
British Food Journal Volume 49 Issue 8 1947
British Food Journal Volume 49 Issue 8 1947
In the good old days, before civilisation and artificial eating habits caught up with mankind, the majority of people in the world got all the Vitamin B and protein their bodies ne...